Literature DB >> 28686730

Correction: Real-time cell toxicity profiling of Tox21 10K compounds reveals cytotoxicity dependent toxicity pathway linkage.

Jui-Hua Hsieh, Ruili Huang, Ja-An Lin, Alexander Sedykh, Jinghua Zhao, Raymond R Tice, Richard S Paules, Menghang Xia, Scott S Auerbach.   

Abstract

[This corrects the article DOI: 10.1371/journal.pone.0177902.].

Entities:  

Year:  2017        PMID: 28686730      PMCID: PMC5501664          DOI: 10.1371/journal.pone.0181291

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.240


The images for Figs 2 and 3 are incorrectly switched. The image that appears as Fig 2 should be Fig 3 and the image that appears as Fig 3 should be Fig 2. The figure captions appear in the correct order.
Fig 2

Examples of two chemicals (digitonin vs. mitomycin C) with different kinetics of cytotoxicity.

Blue: HEK293; red: HepG2. Filled circle (glo); hollow circle (flor); the arrow represents the earliest time interval where the maximum cytotoxic effect was obtained (filled arrow head: glo; hollow arrow head: flor).

Fig 3

Comparison of number of actives in four assays.

The number of actives detected in the four assays at the six different time points. Blue: HEK293 cell line; red: HepG2 cell line. Filled circle: glo assay technology; hollow circle: flor assay technology.

Examples of two chemicals (digitonin vs. mitomycin C) with different kinetics of cytotoxicity.

Blue: HEK293; red: HepG2. Filled circle (glo); hollow circle (flor); the arrow represents the earliest time interval where the maximum cytotoxic effect was obtained (filled arrow head: glo; hollow arrow head: flor).

Comparison of number of actives in four assays.

The number of actives detected in the four assays at the six different time points. Blue: HEK293 cell line; red: HepG2 cell line. Filled circle: glo assay technology; hollow circle: flor assay technology.
  1 in total

1.  Real-time cell toxicity profiling of Tox21 10K compounds reveals cytotoxicity dependent toxicity pathway linkage.

Authors:  Jui-Hua Hsieh; Ruili Huang; Ja-An Lin; Alexander Sedykh; Jinghua Zhao; Raymond R Tice; Richard S Paules; Menghang Xia; Scott S Auerbach
Journal:  PLoS One       Date:  2017-05-22       Impact factor: 3.240

  1 in total
  2 in total

1.  Cytotoxicity Burst? Differentiating Specific from Nonspecific Effects in Tox21 in Vitro Reporter Gene Assays.

Authors:  Beate I Escher; Luise Henneberger; Maria König; Rita Schlichting; Fabian C Fischer
Journal:  Environ Health Perspect       Date:  2020-07-23       Impact factor: 9.031

2.  The repositioning of epigenetic probes/inhibitors identifies new anti-schistosomal lead compounds and chemotherapeutic targets.

Authors:  Kezia C L Whatley; Gilda Padalino; Helen Whiteland; Kathrin K Geyer; Benjamin J Hulme; Iain W Chalmers; Josephine Forde-Thomas; Salvatore Ferla; Andrea Brancale; Karl F Hoffmann
Journal:  PLoS Negl Trop Dis       Date:  2019-11-15
  2 in total

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