Thanh Binh Nguyen1, Pascal Retailleau1. 1. Institut de Chimie des Substances Naturelles, CNRS UPR 2301, Université Paris-Sud , Université Paris-Saclay, 1, avenue de la Terrasse, 91198 Gif-sur-Yvette, France.
Abstract
A catalyst-free, redox-neutral, and completely atom-economical synthesis of sultams by simply heating 2-nitrochalcones with elemental sulfur in 3-picoline or N-methylmorpholine is described. The S-N, C-S, and S═O bonds of the sulfonamide are efficiently formed between the nitrogen atom of the 2-nitro group and the α-carbon of the chalcones and elemental sulfur with the migration of two oxygen atoms from the 2-nitro group to the sulfur atom.
A catalyst-free, redox-neutral, and completely atom-economical synthesis of sultams by simply heating n class="Chemical">2-nitrochalcones with elemental sulfur in 3-picoline or N-methylmorpholine is described. The S-N, C-S, and S═O bonds of the sulfonamide are efficiently formed between the nitrogen atom of the 2-nitro group and the α-carbon of the chalcones and elemental sulfur with the migration of two oxygen atoms from the 2-nitro group to the sulfur atom.
Authors: Mariia O Shyshkina; Dmitry A Lega; Volodymyr D Goryachiy; Ludmila M Shemchuk; Dmitriy V Levashov; Leonid A Shemchuk Journal: Acta Crystallogr E Crystallogr Commun Date: 2021-02-26