Daniel A Galvão1,2, Robert U Newton1,2,3, Afaf Girgis4, Stephen J Lepore5, Anna Stiller6, Cathrine Mihalopoulos7, Robert A Gardiner1,3, Dennis R Taaffe1,2,8, Stefano Occhipinti9, Suzanne K Chambers1,6,9,10. 1. Exercise Medicine Research Institute, Edith Cowan University, Perth, Australia. 2. School of Medical and Health Sciences, Edith Cowan University, Perth, Australia. 3. University of Queensland Centre for Clinical Research, University of Queensland, Brisbane, Australia. 4. Centre for Oncology Education and Research Translation, Ingham Institute for Applied Medical Research, South Western Sydney Clinical School, University of NSW, Sydney, Australia. 5. Department of Social and Behavioral Sciences, Temple University, Philadelphia, PA, USA. 6. Cancer Council Queensland, Brisbane, Australia. 7. Deakin Health Economics, Deakin University, Melbourne, Australia. 8. School of Human Movement and Nutrition Sciences, University of Queensland, Brisbane, Australia. 9. Menzies Health Institute Queensland, Griffith University, Gold Coast, Australia. 10. Prostate Cancer Foundation of Australia, Sydney, Australia.
Abstract
OBJECTIVE: Exercise may reduce morbidity, increase survival, and improve quality of life (QoL) in prostate cancer patients. However, effective ways to encourage exercise outside carefully controlled clinical trials remain uncertain. We evaluated the effectiveness of peer-led self-management for increasing exercise participation in men with localized prostate cancer. METHODS:Four hundred and sixty-three prostate cancer patients from Queensland, Australia were randomized to a monthly telephone-based group peer support for 6 months supported by self-management materials and exercise equipment (INT, n = 232) or usual care (UC, n = 231). Participants were assessed at baseline, 3, 6, and 12 months. Primary outcomes were compliance with exercise guidelines; secondary outcomes were psychological distress and QoL. RESULTS: Patients in INT engaged in more resistance exercise than UC at 3 months (19.4 [95% CI 6.52 to 32.28] min/wk, P = .003) and 6 months (14.6 [95% CI 1.69 to 27.58] min/wk, P = .027); more men achieved sufficient physical activity levels at 3 months (χ2 = 8.89, P = 0.003). There was no difference between groups for aerobic-based activity at any time point nor for resistance exercise time at 12-month follow-up. INT had higher QoL Relationships scores at 3 months (.03 [95% CI .00 to .06], P = .038) compared with UC. Limitation included self-reported assessment of exercise. CONCLUSIONS:Peer-led intervention was effective in increasing patients' resistance exercise participation in the short-to-medium term and in the number of men achieving sufficient activity levels in the short-term; however, this was not accompanied by overall improvements in QoL or psychological distress. Methods to increase effectiveness and maintain long-term adherence require further investigation.
RCT Entities:
OBJECTIVE: Exercise may reduce morbidity, increase survival, and improve quality of life (QoL) in prostate cancerpatients. However, effective ways to encourage exercise outside carefully controlled clinical trials remain uncertain. We evaluated the effectiveness of peer-led self-management for increasing exercise participation in men with localized prostate cancer. METHODS: Four hundred and sixty-three prostate cancerpatients from Queensland, Australia were randomized to a monthly telephone-based group peer support for 6 months supported by self-management materials and exercise equipment (INT, n = 232) or usual care (UC, n = 231). Participants were assessed at baseline, 3, 6, and 12 months. Primary outcomes were compliance with exercise guidelines; secondary outcomes were psychological distress and QoL. RESULTS:Patients in INT engaged in more resistance exercise than UC at 3 months (19.4 [95% CI 6.52 to 32.28] min/wk, P = .003) and 6 months (14.6 [95% CI 1.69 to 27.58] min/wk, P = .027); more men achieved sufficient physical activity levels at 3 months (χ2 = 8.89, P = 0.003). There was no difference between groups for aerobic-based activity at any time point nor for resistance exercise time at 12-month follow-up. INT had higher QoL Relationships scores at 3 months (.03 [95% CI .00 to .06], P = .038) compared with UC. Limitation included self-reported assessment of exercise. CONCLUSIONS: Peer-led intervention was effective in increasing patients' resistance exercise participation in the short-to-medium term and in the number of men achieving sufficient activity levels in the short-term; however, this was not accompanied by overall improvements in QoL or psychological distress. Methods to increase effectiveness and maintain long-term adherence require further investigation.
Authors: Pedro Lopez; Dennis R Taaffe; Robert U Newton; Nigel Spry; Tom Shannon; Mark Frydenberg; Fred Saad; Daniel A Galvão Journal: Eur Urol Open Sci Date: 2020-10-02
Authors: Elochukwu Fortune Ezenwankwo; Portia Motsoeneng; Elizabeth Maria Atterbury; Yumna Albertus; Estelle Victoria Lambert; Delva Shamley Journal: Support Care Cancer Date: 2022-01-21 Impact factor: 3.603
Authors: Chloe Grimmett; Teresa Corbett; Jennifer Brunet; Jonathan Shepherd; Bernardine M Pinto; Carl R May; Claire Foster Journal: Int J Behav Nutr Phys Act Date: 2019-04-27 Impact factor: 6.457
Authors: Holly E L Evans; Cynthia C Forbes; Daniel A Galvão; Corneel Vandelanotte; Robert U Newton; Gary Wittert; Suzanne Chambers; Andrew D Vincent; Ganessan Kichenadasse; Nicholas Brook; Danielle Girard; Camille E Short Journal: Pilot Feasibility Stud Date: 2021-01-11
Authors: Teresa Lam; Birinder Cheema; Amy Hayden; Stephen R Lord; Howard Gurney; Shivanjini Gounden; Navneeta Reddy; Haleh Shahidipour; Scott Read; Glenn Stone; Mark McLean; Vita Birzniece Journal: Sports Med Open Date: 2020-12-14
Authors: Rebecca R Turner; Liz Steed; Helen Quirk; Rosa U Greasley; John M Saxton; Stephanie Jc Taylor; Derek J Rosario; Mohamed A Thaha; Liam Bourke Journal: Cochrane Database Syst Rev Date: 2018-09-19
Authors: A Baudot; N Barth; C Colas; M Garros; A Garcin; M Oriol; F Roche; F Chauvin; N Mottet; D Hupin Journal: Pilot Feasibility Stud Date: 2022-01-21