Literature DB >> 28685581

Assessment of monocyte to high density lipoprotein cholesterol ratio and lymphocyte-to-monocyte ratio in patients with metabolic syndrome.

Demir Vahit1, Mehmet Kadri Akboga2, Yilmaz Samet3, Ede Hüseyin1.   

Abstract

AIM: We aimed to investigate the relationships between metabolic syndrome (MS) and monocyte to high density lipoprotein cholesterol ratio (MHR) and lymphocyte-to-monocyte ratio (LMR).
METHODS: 762 patients (n = 371 MS present and n = 391 MS absent) were enrolled.
RESULTS: MHR was significantly higher [13.9 (10.5-18.1) vs 11.1 (8.0-14.8); p < 0.001], whereas LMR was significantly lower [4.5 (3.6-5.7) vs 3.6 (2.9-4.8); p < 0.001] in patients with MS. LMR [OR: 0.796 (95% CI): 0.711-0.892); p < 0.001], MHR [OR: 1.052 (95% CI: 1.018-1.088); p = 0.003] and C-reactive protein [OR: 1.048 (95% CI: 1.032-1.065); p < 0.001] remained as independent variables for the presence of MS.
CONCLUSION: The present study shows that both LMR and MHR may be novel and useful indicators of MS.

Entities:  

Keywords:  lymphocyte-to-monocyte ratio; metabolic syndrome; monocyte to HDL cholesterol ratio

Mesh:

Substances:

Year:  2017        PMID: 28685581     DOI: 10.2217/bmm-2016-0380

Source DB:  PubMed          Journal:  Biomark Med        ISSN: 1752-0363            Impact factor:   2.851


  18 in total

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