Literature DB >> 28685189

Mesencephalic astrocyte-derived neurotrophic factor and its role in nervous system disease.

Zhu Li-Na1, Chen Deng1, Xu Da1, Chen Si-Han1, Wang Hai-Jiao1, Liu Ling2.   

Abstract

Mesencephalic astrocyte-derived neurotrophic factor (MANF) is a member of the novel evolutionary conserved neurotrophic factor (NTF) family. MANF has a unique structure and an unparalleled dual mode of action that differs from other known NTFs. Recent studies have shown that MANF protects cells from endoplasmic reticulum stress. In addition, an increasing number of studies have found MANF plays an important role in nervous system disease. This review focuses on MANF, summarizing its unique structure, potential signaling pathway, and role in neurological disease.

Entities:  

Keywords:  MANF; NTF; Neurological disease

Mesh：

Substances：

Year:  2017        PMID： 28685189     DOI： 10.1007/s10072-017-3042-2

Source DB:  PubMed          Journal:  Neurol Sci        ISSN： 1590-1874            Impact factor:   3.307


  40 in total

1.  SAP - a putative DNA-binding motif involved in chromosomal organization.

Authors:  L Aravind; E V Koonin
Journal:  Trends Biochem Sci       Date:  2000-03       Impact factor: 13.807

2.  Mesencephalic astrocyte-derived neurotrophic factor alleviated 6-OHDA-induced cell damage via ROS-AMPK/mTOR mediated autophagic inhibition.

Authors:  Jingxing Zhang; Qiong Cai; Ming Jiang; Yigang Liu; Hua Gu; Jia Guo; Hui Sun; Jianmin Fang; Lingjing Jin
Journal:  Exp Gerontol       Date:  2017-01-15       Impact factor: 4.032

3.  The Solution Structure and Dynamics of Full-length Human Cerebral Dopamine Neurotrophic Factor and Its Neuroprotective Role against α-Synuclein Oligomers.

Authors:  Cristiane Latge; Katia M S Cabral; Guilherme A P de Oliveira; Diana P Raymundo; Julia A Freitas; Laizes Johanson; Luciana F Romão; Fernando L Palhano; Torsten Herrmann; Marcius S Almeida; Debora Foguel
Journal:  J Biol Chem       Date:  2015-07-06       Impact factor: 5.157

4.  Chronic restraint stress promotes learning and memory impairment due to enhanced neuronal endoplasmic reticulum stress in the frontal cortex and hippocampus in male mice.

Authors:  Rong-Rong Huang; Wen Hu; Yan-Yan Yin; Yu-Chan Wang; Wei-Ping Li; Wei-Zu Li
Journal:  Int J Mol Med       Date:  2014-12-05       Impact factor: 4.101

5.  Armet, a UPR-upregulated protein, inhibits cell proliferation and ER stress-induced cell death.

Authors:  Andria Apostolou; Yuxian Shen; Yan Liang; Jun Luo; Shengyun Fang
Journal:  Exp Cell Res       Date:  2008-05-13       Impact factor: 3.905

6.  Mesencephalic astrocyte-derived neurotrophic factor is an ischemia-inducible secreted endoplasmic reticulum stress response protein in the heart.

Authors:  Archana Tadimalla; Peter J Belmont; Donna J Thuerauf; Matthew S Glassy; Joshua J Martindale; Natalie Gude; Mark A Sussman; Christopher C Glembotski
Journal:  Circ Res       Date:  2008-10-16       Impact factor: 17.367

7.  Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo.

Authors:  Päivi Lindholm; Merja H Voutilainen; Juha Laurén; Johan Peränen; Veli-Matti Leppänen; Jaan-Olle Andressoo; Maria Lindahl; Sanna Janhunen; Nisse Kalkkinen; Tõnis Timmusk; Raimo K Tuominen; Mart Saarma
Journal:  Nature       Date:  2007-07-05       Impact factor: 49.962

8.  MANF is widely expressed in mammalian tissues and differently regulated after ischemic and epileptic insults in rodent brain.

Authors:  Päivi Lindholm; Johan Peränen; Jaan-Olle Andressoo; Nisse Kalkkinen; Zaal Kokaia; Olle Lindvall; Tõnis Timmusk; Mart Saarma
Journal:  Mol Cell Neurosci       Date:  2008-07-30       Impact factor: 4.314

9.  Characterization of the structural and functional determinants of MANF/CDNF in Drosophila in vivo model.

Authors:  Riitta Lindström; Päivi Lindholm; Jukka Kallijärvi; Li-Ying Yu; T Petteri Piepponen; Urmas Arumäe; Mart Saarma; Tapio I Heino
Journal:  PLoS One       Date:  2013-09-03       Impact factor: 3.240

10.  Role of two sequence motifs of mesencephalic astrocyte-derived neurotrophic factor in its survival-promoting activity.

Authors:  K Mätlik; Li-ying Yu; A Eesmaa; M Hellman; P Lindholm; J Peränen; E Galli; J Anttila; M Saarma; P Permi; M Airavaara; U Arumäe
Journal:  Cell Death Dis       Date:  2015-12-31       Impact factor: 8.469
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  3 in total

Review 1.  Signaling pathways in obesity: mechanisms and therapeutic interventions.

Authors:  Xue Wen; Bohan Zhang; Beiyi Wu; Haitao Xiao; Zehua Li; Ruoyu Li; Xuewen Xu; Tao Li
Journal:  Signal Transduct Target Ther       Date:  2022-08-28

2.  Analysis of the clinical features of early Parkinson's disease with comparatively integrated intestinal function.

Authors:  Xiaoxue Guan; Yuchan Wang; Qun Li; Ming Wei; Lili Chen; Oumei Cheng
Journal:  Neurol Sci       Date:  2018-07-17       Impact factor: 3.307

Review 3.  Novel therapeutic modulators of astrocytes for hydrocephalus.

Authors:  Yijian Yang; Chuansen Wang; Rui Chen; Yuchang Wang; Changwu Tan; Jingping Liu; Qinghua Zhang; Gelei Xiao
Journal:  Front Mol Neurosci       Date:  2022-09-26       Impact factor: 6.261
  3 in total

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