María de Las Aguas Robustillo Cortés1, Ramón Morillo Verdugo2, Esther María Barreiro Fernández3, Ascensión Pavón Plata4, Patricia Monje Agudo5. 1. Clinical Management Unit of Pharmacy. Hospital Universitario de Valme. Healthcare Management Area: South Seville.. aguasrobustillo@gmail.com. 2. Clinical Management Unit of Pharmacy. Hospital Universitario de Valme. Healthcare Management Area: South Seville.Hospital Universitario de Valme. AGS Sur de Sevilla. ralejandro.morillo.sspa@juntadeandalucia.es. 3. School of Pharmacy. Universidad de Sevilla.. estherbf@hotmail.es. 4. School of Pharmacy. Universidad de Sevilla.. censipavon15@gmail.com. 5. Clinical Management Unit of Pharmacy. Hospital Regional de Málaga.. patriciamonjeagudo@hotmail.com.
Abstract
OBJECTIVE: To determine the variation in the pharmacotherapy complexity index in HIV+ patients after hospital admission. METHOD: A retrospective, single-center study with HIV+ patients on antiretroviral treatment (ART) who were admitted to hospital between 2008 and 2015 were conducted. Demographic, analytical, clinical and pharmacotherapy variables were collected, as well as those about the use of healthcare resources. The primary endpoint was the variation in the overall complexity index after a hospital admission, measured through the MRCI tool (University of Colorado). There was also an analysis of the variation in adherence to ART, and of the causes that led to an increase in pharmacotherapy complexity after hospitalization. RESULTS: The study included 146 patients (84.9% male) with 45.3 ± 9.1 years as mean age; 30.8% of these patients had experienced an admission to hospital in the previous year, with a median stay of seven days (IQR: 4-12,5). The mean overall complexity before hospital admission was 14.5 ± 7.2 vs. 16.5 ± 8.0 after admission, with a significant difference (1.97 [CI = 0.85;3.09]). The percentage of patients adherent to ART before admission was 58.3% vs. 41.8% after admission (p = 0.023). The only factor associated to an increase in complexity was having five or more chronic drugs prescribed before admission (OR = 3.146 [1.045-9.471]). CONCLUSION: The overall pharmacotherapy complexity increased after hospital admission, reducing the adherence to ART. Chronic treatment prescribed before admission was the only factor associated with an increase in complexity after admission. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.
OBJECTIVE: To determine the variation in the pharmacotherapy complexity index in HIV+ patients after hospital admission. METHOD: A retrospective, single-center study with HIV+ patients on antiretroviral treatment (ART) who were admitted to hospital between 2008 and 2015 were conducted. Demographic, analytical, clinical and pharmacotherapy variables were collected, as well as those about the use of healthcare resources. The primary endpoint was the variation in the overall complexity index after a hospital admission, measured through the MRCI tool (University of Colorado). There was also an analysis of the variation in adherence to ART, and of the causes that led to an increase in pharmacotherapy complexity after hospitalization. RESULTS: The study included 146 patients (84.9% male) with 45.3 ± 9.1 years as mean age; 30.8% of these patients had experienced an admission to hospital in the previous year, with a median stay of seven days (IQR: 4-12,5). The mean overall complexity before hospital admission was 14.5 ± 7.2 vs. 16.5 ± 8.0 after admission, with a significant difference (1.97 [CI = 0.85;3.09]). The percentage of patients adherent to ART before admission was 58.3% vs. 41.8% after admission (p = 0.023). The only factor associated to an increase in complexity was having five or more chronic drugs prescribed before admission (OR = 3.146 [1.045-9.471]). CONCLUSION: The overall pharmacotherapy complexity increased after hospital admission, reducing the adherence to ART. Chronic treatment prescribed before admission was the only factor associated with an increase in complexity after admission. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.
Authors: M Gracia Cantillana-Suárez; Maria de Las Aguas Robustillo-Cortés; Antonio Gutiérrez-Pizarraya; Ramón Morillo-Verdugo Journal: Eur J Hosp Pharm Date: 2021-02-24
Authors: José Manuel Vinuesa-Hernando; Mercedes Gimeno-Gracia; Sara Malo; Isabel Sanjoaquin-Conde; María José Crusells-Canales; Santiago Letona-Carbajo; Raquel Gracia-Piquer Journal: Int J Clin Pharm Date: 2021-02-04