| Literature DB >> 28683356 |
Sara Roberta Dos Santos1, Camila Maria de Sousa Lacerda2, Iêda Mendes Ferreira3, André Luís Branco de Barros4, Simone Odília Fernandes5, Valbert Nascimento Cardoso6, Antero Silva Ribeiro de Andrade7.
Abstract
Staphylococcus aureus is a specie of great medical importance associated with many infections as bacteremia and infective endocarditis as well as osteoarticular, skin and soft tissue, pleuropulmonary, and device related infections. Early identification of infectious foci is crucial for successful treatment. Scintigraphy could contribute to this purpose since specific radiotracers were available. Aptamers due to their high specificity have great potential for radiopharmaceuticals development. In the present study scintigraphic images of S. aureus infectious foci were obtained using specific S. aureus aptamers radiolabeled with 99mTc.Entities:
Keywords: Aptamer; Bacterial infection; Diagnosis; Radiopharmaceutical; Technetium-99m
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Year: 2017 PMID： 28683356 DOI： 10.1016/j.apradiso.2017.06.043
Source DB: PubMed Journal: Appl Radiat Isot ISSN： 0969-8043 Impact factor: 1.513