Literature DB >> 28682723

Treating Giant Congenital Nevus With Integra Dermal Regeneration Template in a 9-Year-Old Girl.

Zoran Barcot1, Inga Dakovic Bacalja2, Bozidar Zupancic3, Vedran Bacalja4.   

Abstract

Integra dermal regeneration template has been well established in treating deep extensive burns, but there are very few cases reported of treating large full-thickness skin defects such as giant nevi. Apart from psychological and cosmetic burdens, the giant congenital nevus carries increased risk of malignant alteration. We present the case of a 9-year-old girl with a giant congenital nevus on her left lower leg. A total excision was done and she was successfully treated with Integra (LifeSciences Corp, Plainsboro, NJ). Three weeks later, a thin split-skin graft was applied over the neodermal skin layer. The takeoff was 91%. Protected with the silver wound dressing, the rest of the wound healed. A donor site morbidity was minimal, and the final result was excellent both in aesthetic and functional aspects.

Entities:  

Keywords:  Integra; dermal substitute; giant nevus; lower extremity reconstruction; pediatric

Mesh:

Substances:

Year:  2017        PMID: 28682723     DOI: 10.1177/1534734617702259

Source DB:  PubMed          Journal:  Int J Low Extrem Wounds        ISSN: 1534-7346            Impact factor:   2.057


  3 in total

Review 1.  Use of Integra for Reconstruction after Nevi Resection: A Systematic Review and Pooled Analysis of Reported Cases.

Authors:  Jude Opoku-Agyeman; Kayla Humenansky; Wellington Davis; Paul Glat
Journal:  Surg Res Pract       Date:  2019-10-09

2.  Giant Congenital Melanocytic Nevus in a Chinese Newborn.

Authors:  Weizhao Lin; Yixuan Zhou; Ruiman Li
Journal:  Clin Cosmet Investig Dermatol       Date:  2021-05-26

3.  Regeneration mechanism for skin and peripheral nerves clarified at the organ and molecular scales.

Authors:  Ioannis V Yannas; Dimitrios S Tzeranis; Peter T C So
Journal:  Curr Opin Biomed Eng       Date:  2018-06
  3 in total

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