BACKGROUND: Breastfeeding is a widely encouraged practice due to its benefits for mother and the infant. Little is known about the impact of disease states, such as kidney dysfunction and childbirth complications, on the composition of breast milk. METHODS: We describe a case of a 35-year-old woman who suffered a postpartum hemorrhage, was administered a contrast dye prior to computer tomography, and developed an acute kidney injury. Using nuclear magnetic resonance spectrometry, we measured composition of milk in acute kidney injury. The amount of dye secreted into milk was determined using a spectroscopic assay. RESULTS: Here we show that acute kidney injury results in changes in milk composition, but it does not significantly affect major macronutrients. We also determine that iodinated computer tomography contrast dye does not accumulate in milk in appreciable amounts. CONCLUSION: Acute kidney injury has impact on breast milk. Intravenous administration of computer tomography contrast dye does not result in significantly elevated levels in milk.
BACKGROUND: Breastfeeding is a widely encouraged practice due to its benefits for mother and the infant. Little is known about the impact of disease states, such as kidney dysfunction and childbirth complications, on the composition of breast milk. METHODS: We describe a case of a 35-year-old woman who suffered a postpartum hemorrhage, was administered a contrast dye prior to computer tomography, and developed an acute kidney injury. Using nuclear magnetic resonance spectrometry, we measured composition of milk in acute kidney injury. The amount of dye secreted into milk was determined using a spectroscopic assay. RESULTS: Here we show that acute kidney injury results in changes in milk composition, but it does not significantly affect major macronutrients. We also determine that iodinated computer tomography contrast dye does not accumulate in milk in appreciable amounts. CONCLUSION:Acute kidney injury has impact on breast milk. Intravenous administration of computer tomography contrast dye does not result in significantly elevated levels in milk.
Authors: Jennifer T Smilowitz; Aifric O'Sullivan; Daniela Barile; J Bruce German; Bo Lönnerdal; Carolyn M Slupsky Journal: J Nutr Date: 2013-09-11 Impact factor: 4.798
Authors: M C Neville; J C Allen; P C Archer; C E Casey; J Seacat; R P Keller; V Lutes; J Rasbach; M Neifert Journal: Am J Clin Nutr Date: 1991-07 Impact factor: 7.045
Authors: Michael S Balzer; Mechthild M Gross; Ralf Lichtinghagen; Hermann Haller; Roland Schmitt Journal: PLoS One Date: 2015-11-16 Impact factor: 3.240