L Barbera1, C Zwaal2, D Elterman3, K McPherson4, W Wolfman5, A Katz6, A Matthew3. 1. Department of Radiation Oncology, University of Toronto, Toronto. 2. Program in Evidence-Based Care, Cancer Care Ontario, Hamilton. 3. Department of Surgery, Division of Urology, University of Toronto, Toronto. 4. Patient and Family Advisory Council, Cancer Care Ontario, Hamilton; and. 5. Department of Obstetrics and Gynecology, University of Toronto, Toronto, ON; and. 6. CancerCare Manitoba, Winnipeg, MB.
Abstract
BACKGROUND: Sexual dysfunction in people with cancer is a significant problem. The present clinical practice guideline makes recommendations to improve sexual function in people with cancer. METHODS: This guideline was undertaken by the Interventions to Address Sexual Problems in People with Cancer Expert Panel, a group organized by the Program in Evidence-Based Care (pebc). Consistent with the pebc standardized approach, a systematic search was conducted for existing guidelines, and the literature in medline and embase for the years 2003-2015 was systematically searched for both systematic reviews and primary literature. Evidence found for men and for women was evaluated separately, and no restrictions were placed on cancer type or study design. Content and methodology experts performed an internal review of the resulting draft recommendations, which was followed by an external review by targeted experts and intended users. RESULTS: The search identified 4 existing guidelines, 13 systematic reviews, and 103 studies with relevance to the topic. The present guideline provides one overarching recommendation concerning the discussion of sexual health and dysfunction, which is aimed at all people with cancer. Eleven additional recommendations made separately for men and women deal with issues such as sexual response, body image, intimacy and relationships, overall sexual functioning and satisfaction, and vasomotor and genital symptoms. CONCLUSIONS: To our knowledge this clinical practice guideline is the first to comprehensively evaluate interventions for the improvement of sexual problems in people with cancer. The guideline will be a valuable resource to support practitioners and clinics in addressing sexuality in cancer survivors.
BACKGROUND:Sexual dysfunction in people with cancer is a significant problem. The present clinical practice guideline makes recommendations to improve sexual function in people with cancer. METHODS: This guideline was undertaken by the Interventions to Address Sexual Problems in People with Cancer Expert Panel, a group organized by the Program in Evidence-Based Care (pebc). Consistent with the pebc standardized approach, a systematic search was conducted for existing guidelines, and the literature in medline and embase for the years 2003-2015 was systematically searched for both systematic reviews and primary literature. Evidence found for men and for women was evaluated separately, and no restrictions were placed on cancer type or study design. Content and methodology experts performed an internal review of the resulting draft recommendations, which was followed by an external review by targeted experts and intended users. RESULTS: The search identified 4 existing guidelines, 13 systematic reviews, and 103 studies with relevance to the topic. The present guideline provides one overarching recommendation concerning the discussion of sexual health and dysfunction, which is aimed at all people with cancer. Eleven additional recommendations made separately for men and women deal with issues such as sexual response, body image, intimacy and relationships, overall sexual functioning and satisfaction, and vasomotor and genital symptoms. CONCLUSIONS: To our knowledge this clinical practice guideline is the first to comprehensively evaluate interventions for the improvement of sexual problems in people with cancer. The guideline will be a valuable resource to support practitioners and clinics in addressing sexuality in cancer survivors.
Entities:
Keywords:
Sexual problems; interventions; practice guidelines
Authors: Melissa C Brouwers; Michelle E Kho; George P Browman; Jako S Burgers; Francoise Cluzeau; Gene Feder; Béatrice Fervers; Ian D Graham; Jeremy Grimshaw; Steven E Hanna; Peter Littlejohns; Julie Makarski; Louise Zitzelsberger Journal: CMAJ Date: 2010-07-05 Impact factor: 8.262
Authors: Mara Z Vitolins; Leah Griffin; W Vic Tomlinson; Jacqueline Vuky; Paul T Adams; Dawn Moose; Bart Frizzell; Glenn J Lesser; Michelle Naughton; James E Radford; Edward G Shaw Journal: J Clin Oncol Date: 2013-09-30 Impact factor: 44.544
Authors: Francesco Montorsi; Gerald Brock; Jay Lee; JoAnn Shapiro; Hendrik Van Poppel; Markus Graefen; Christian Stief Journal: Eur Urol Date: 2008-07-09 Impact factor: 20.096
Authors: Adele Duimering; Lauren M Walker; Jill Turner; Elisha Andrews-Lepine; Amy Driga; Ashley Ayume; John W Robinson; Ericka Wiebe Journal: Support Care Cancer Date: 2019-08-19 Impact factor: 3.603
Authors: Karen Roberts; Travis Chong; Emma Hollands; Jason Tan; Ganendra Raj Kader Ali Mohan; Paul A Cohen Journal: Support Care Cancer Date: 2019-05-18 Impact factor: 3.603
Authors: David-Dan Nguyen; Alejandro Berlin; Andrew G Matthew; Nathan Perlis; Dean S Elterman Journal: Int J Impot Res Date: 2021-01-06 Impact factor: 2.896
Authors: Debra L Barton; Stephanie L Pugh; Patricia A Ganz; Steven C Plaxe; Bridget F Koontz; Jeanne Carter; Natalya Greyz-Yusupov; Seth J Page; Kendrith M Rowland; Ernie P Balcueva; Sobia Nabeel; Jack B Basil; Matthew L Hill; Carolyn Y Muller; Maria C Bell; Snehal Deshmukh; Lisa A Kachnic Journal: J Clin Oncol Date: 2021-12-09 Impact factor: 44.544
Authors: Kelly M Shaffer; Erin Kennedy; Jillian V Glazer; Anita H Clayton; Wendy Cohn; Jennifer Barsky Reese; Trish A Millard; Karen S Ingersoll; Lee M Ritterband; Shayna Showalter Journal: Support Care Cancer Date: 2022-02-17 Impact factor: 3.359
Authors: Natasha N Frederick; Vicky Lehmann; Astrid Ahler; Kristen Carpenter; Brooke Cherven; James L Klosky; Leena Nahata; Gwendolyn P Quinn Journal: Pediatr Blood Cancer Date: 2021-12-06 Impact factor: 3.838
Authors: Jana Pöttgen; Wim van de Vis; An van Nunen; Anita Rose; Jannie Engelbrecht; Michelle Pirard; Stephanie Lau; Christoph Heesen; Sascha Köpke Journal: Int J MS Care Date: 2020-12-28
Authors: Kari L Bjornard; Carrie R Howell; James L Klosky; Wassim Chemaitilly; Deo Kumar Srivastava; Tara M Brinkman; Daniel M Green; Victoria W Willard; Lisa M Jacola; Matthew J Krasin; Melissa M Hudson; Leslie L Robison; Kirsten K Ness Journal: J Sex Med Date: 2020-07-25 Impact factor: 3.802
Authors: Rieky E Dikmans; Esmée M Krouwel; Mahsa Ghasemi; Tim C van de Grift; Mark-Bram Bouman; Marco J P F Ritt; Henk W Elzevier; Margriet G Mullender Journal: Eur J Plast Surg Date: 2018-08-18
Authors: Karen L Syrjala; Hélène Schoemans; Jean C Yi; Shelby L Langer; Ahona Mukherjee; Lynn Onstad; Stephanie J Lee Journal: Transplant Cell Ther Date: 2020-09-29