Literature DB >> 28677496

Metabolic Syndrome, Dyslipidemia and Regulation of Lipoprotein Metabolism.

Jahangir Iqbal1, Ali Al Qarni1, Abbas Hawwari1, Ahmad F Alghanem1, Gasmelseed Ahmed1.   

Abstract

BACKGROUND: Metabolic syndrome is associated with increased risk for both type 2 diabetes and cardiovascular disease. Development of these pathologies is associated with the disorders of lipid and lipoprotein metabolism. Dyslipidemia leads to the overproduction of potentially atherogenic lipid and lipoproteins. Furthermore, there is a decrease in the levels of high-density lipoproteins and an increase in the levels of remnant and small dense LDL particles.
CONCLUSION: In the current review, we have discussed the pathophysiology of lipoprotein biosynthesis and metabolism in the metabolic syndrome. Finally, we describe regulation of lipoprotein metabolism which may be used as a potential target for treating dyslipidemia in metabolic syndrome. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Entities:  

Keywords:  Metabolic syndrome; dyslipidemia; insulin resistance; lipid metabolism; lipoprotein biosynthesis; microRNA.

Mesh:

Substances:

Year:  2018        PMID: 28677496     DOI: 10.2174/1573399813666170705161039

Source DB:  PubMed          Journal:  Curr Diabetes Rev        ISSN: 1573-3998


  19 in total

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2.  PoLA/CFPiP/PCS/PSLD/PSD/PSH guidelines on diagnosis and therapy of lipid disorders in Poland 2021.

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Journal:  Front Endocrinol (Lausanne)       Date:  2022-05-16       Impact factor: 6.055

Review 4.  The Role of MicroRNAs in Hyperlipidemia: From Pathogenesis to Therapeutical Application.

Authors:  Yu Xiang; Li Mao; Mei-Ling Zuo; Gui-Lin Song; Li-Ming Tan; Zhong-Bao Yang
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5.  LRP1-Mediated AggLDL Endocytosis Promotes Cholesteryl Ester Accumulation and Impairs Insulin Response in HL-1 Cells.

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7.  Health behaviors and metabolic risk factors are associated with dyslipidemia in ethnic Miao Chinese adults: the China multi-ethnic cohort study.

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8.  Aberrant expression of HDL-bound microRNA induced by a high-fat diet in a pig model: implications in the pathogenesis of dyslipidaemia.

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Review 9.  Green Tea Catechins: Their Use in Treating and Preventing Infectious Diseases.

Authors:  Wanda C Reygaert
Journal:  Biomed Res Int       Date:  2018-07-17       Impact factor: 3.411

Review 10.  The potential role of sesquiterpene lactones isolated from medicinal plants in the treatment of the metabolic syndrome - A review.

Authors:  Anuar Salazar-Gómez; Julio C Ontiveros-Rodríguez; Saudy S Pablo-Pérez; M Elena Vargas-Díaz; Leticia Garduño-Siciliano
Journal:  S Afr J Bot       Date:  2020-09-16       Impact factor: 2.315

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