Literature DB >> 28675078

Evaluation of the Parkinson's KinetiGraph in monitoring and managing Parkinson's disease.

Parisa Farzanehfar1, Malcolm Horne1.   

Abstract

INTRODUCTION: While objective measurement is routine in clinical care of most conditions, this has not been the case for Parkinson's Disease. Recent innovations make objective measurement in Parkinson's Disease possible and its utility and how this should be assessed is discussed here. Areas covered: Whilst therapies are effective in Parkinson's Disease, symptoms fluctuate in relation to treatment over the course of the day. Objective measurement makes it possible to assess symptom control, whether treatment is required and whether it achieved control. Objective measurement makes it possible to consider targets for therapeutic control and to begin an assessment of the value of improved control. Evidence for the effect of improved measurement on outcomes is only beginning to emerge. As symptom severity relates to quality of life and costs, reducing clinical scores and fluctuations through objective measurement is in the interest of both the patient and the health system. Expert commentary: In broad terms objective measurement should be used to identify patients whose symptoms lie outside the target range and then to assess whether therapy was effective in bringing them into control. While this is relevant to all stages of Parkinson's Disease specific clinical situations where this had greatest impact are discussed.

Entities:  

Keywords:  PKG; Parkinson’s Disease; bradykinesia; dyskinesia; measurement; outcomes; quality of life

Mesh:

Year:  2017        PMID: 28675078     DOI: 10.1080/17434440.2017.1349608

Source DB:  PubMed          Journal:  Expert Rev Med Devices        ISSN: 1743-4440            Impact factor:   3.166


  8 in total

1.  "Does the Response to Morning Medication Predict the ADL-Level of the Day in Parkinson's Disease?"

Authors:  Trine Hørmann Thomsen; Troels Wesenberg Kjær; Lene Bastrup Jørgensen; Anita Haahr; Kristian Winge
Journal:  Parkinsons Dis       Date:  2020-07-27

Review 2.  Point of view: Wearable systems for at-home monitoring of motor complications in Parkinson's disease should deliver clinically actionable information.

Authors:  Behnaz Ghoraani; James E Galvin; Joohi Jimenez-Shahed
Journal:  Parkinsonism Relat Disord       Date:  2021-01-30       Impact factor: 4.891

Review 3.  Precompetitive Consensus Building to Facilitate the Use of Digital Health Technologies to Support Parkinson Disease Drug Development through Regulatory Science.

Authors:  Diane Stephenson; Robert Alexander; Varun Aggarwal; Reham Badawy; Lisa Bain; Roopal Bhatnagar; Bastiaan R Bloem; Babak Boroojerdi; Jackson Burton; Jesse M Cedarbaum; Josh Cosman; David T Dexter; Marissa Dockendorf; E Ray Dorsey; Ariel V Dowling; Luc J W Evers; Katherine Fisher; Mark Frasier; Luis Garcia-Gancedo; Jennifer C Goldsack; Derek Hill; Janice Hitchcock; Michele T Hu; Michael P Lawton; Susan J Lee; Michael Lindemann; Ken Marek; Nitin Mehrotra; Marjan J Meinders; Michael Minchik; Lauren Oliva; Klaus Romero; George Roussos; Robert Rubens; Sakshi Sadar; Joseph Scheeren; Eiichi Sengoku; Tanya Simuni; Glenn Stebbins; Kirsten I Taylor; Beatrice Yang; Neta Zach
Journal:  Digit Biomark       Date:  2020-11-26

4.  CDNF Protein Therapy in Parkinson's Disease.

Authors:  Henri J Huttunen; Mart Saarma
Journal:  Cell Transplant       Date:  2019-04-04       Impact factor: 4.064

5.  Prediction of the Levodopa Challenge Test in Parkinson's Disease Using Data from a Wrist-Worn Sensor.

Authors:  Hamid Khodakarami; Lucia Ricciardi; Maria Fiorella Contarino; Rajesh Pahwa; Kelly E Lyons; Victor J Geraedts; Francesca Morgante; Alison Leake; Dominic Paviour; Andrea De Angelis; Malcolm Horne
Journal:  Sensors (Basel)       Date:  2019-11-25       Impact factor: 3.576

6.  A blinded, controlled trial of objective measurement in Parkinson's disease.

Authors:  Holly Woodrow; Malcolm K Horne; Chathurini V Fernando; Katya E Kotschet
Journal:  NPJ Parkinsons Dis       Date:  2020-11-20

7.  Toward Improved Treatment and Empowerment of Individuals With Parkinson Disease: Design and Evaluation of an Internet of Things System.

Authors:  Liran Karni; Ilir Jusufi; Dag Nyholm; Gunnar Oskar Klein; Mevludin Memedi
Journal:  JMIR Form Res       Date:  2022-06-09

8.  Objective measurement in routine care of people with Parkinson's disease improves outcomes.

Authors:  Parisa Farzanehfar; Holly Woodrow; Michelle Braybrook; Sarah McGregor; Andrew Evans; Frank Nicklason; Malcolm Horne
Journal:  NPJ Parkinsons Dis       Date:  2018-04-03
  8 in total

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