Literature DB >> 28669007

Nephrocalcinosis in a young male with anorexia nervosa.

Nicholas Chadi1, Simon Carter2, Robert P Y Loung3, Michelle Gould4, Katherine Hick3.   

Abstract

Nephrocalcinosis (NC) has been described as a long-term complication of anorexia nervosa (AN). This is the first report of this complication in an adolescent male patient. We describe the case of a 12-year-old male with AN who presented with acute food restriction and excessive exercising leading to three inpatient admissions. The patient experienced an isolated episode of dysuria and hematuria while on calcium and vitamin D supplementation. Investigations revealed hypophosphatemia, hypercalciuria and mild NC. Follow-up confirmed the presence of NC and possible nephrolithiasis (NL). We discuss the pathophysiology and risk factors of NC and NL in the context of an early presentation of AN. We suggest fluid intake should be liberalized under observation and calcium and vitamin D supplementation should be initiated with caution in patients presenting with AN and risk factors for NC and NL.

Entities:  

Keywords:  Adolescent; Anorexia nervosa; Eating disorders; Male; Nephrocalcinosis

Year:  2017        PMID: 28669007      PMCID: PMC5694405          DOI: 10.1007/s13730-017-0267-0

Source DB:  PubMed          Journal:  CEN Case Rep        ISSN: 2192-4449


  15 in total

1.  Anorexia nervosa: an important cause of chronic tubulointerstitial nephropathy.

Authors:  Y Arimura; H Tanaka; T Yoshida; M Shinozaki; T Yanagida; T Ando; H Hirakata; M Fujishima
Journal:  Nephrol Dial Transplant       Date:  1999-04       Impact factor: 5.992

2.  Severe renal failure and nephrocalcinosis in anorexia nervosa.

Authors:  Huy A Tran
Journal:  Med J Aust       Date:  2006-01-02       Impact factor: 7.738

3.  Anorexia nervosa and senna misuse: nephrocalcinosis, digital clubbing and hypertrophic osteoarthropathy.

Authors:  Andy K H Lim; David H Hooke; Peter G Kerr
Journal:  Med J Aust       Date:  2008-01-21       Impact factor: 7.738

4.  End-stage renal disease (ESRD) in patients with eating disorders.

Authors:  E M Abdel-Rahman; A V Moorthy
Journal:  Clin Nephrol       Date:  1997-02       Impact factor: 0.975

5.  Mutations in CYP24A1 and idiopathic infantile hypercalcemia.

Authors:  Karl P Schlingmann; Martin Kaufmann; Stefanie Weber; Andrew Irwin; Caroline Goos; Ulrike John; Joachim Misselwitz; Günter Klaus; Eberhard Kuwertz-Bröking; Henry Fehrenbach; Anne M Wingen; Tülay Güran; Joost G Hoenderop; René J Bindels; David E Prosser; Glenville Jones; Martin Konrad
Journal:  N Engl J Med       Date:  2011-06-15       Impact factor: 91.245

6.  Factors related to renal dysfunction in patients with anorexia nervosa.

Authors:  S Takakura; T Nozaki; Y Nomura; C Koreeda; H Urabe; K Kawai; M Takii; C Kubo
Journal:  Eat Weight Disord       Date:  2006-06       Impact factor: 4.652

Review 7.  Anorexia nervosa and the kidney.

Authors:  Antoine Bouquegneau; Bernard E Dubois; Jean-Marie Krzesinski; Pierre Delanaye
Journal:  Am J Kidney Dis       Date:  2012-05-19       Impact factor: 8.860

Review 8.  The medical complications of anorexia nervosa.

Authors:  C W Sharp; C P Freeman
Journal:  Br J Psychiatry       Date:  1993-04       Impact factor: 9.319

9.  Renal disease and dysfunction in two patients with anorexia nervosa.

Authors:  A W Brotman; T A Stern; D L Brotman
Journal:  J Clin Psychiatry       Date:  1986-08       Impact factor: 4.384

Review 10.  Laxative abuse, eating disorders, and kidney stones: a case report and review of the literature.

Authors:  David E Leaf; Phillip R Bukberg; David S Goldfarb
Journal:  Am J Kidney Dis       Date:  2012-05-04       Impact factor: 8.860

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