Literature DB >> 28668341

Exposure assessment using human biomonitoring for glyphosate and fluroxypyr users in amenity horticulture.

Alison Connolly1, Kate Jones2, Karen S Galea3, Ioannis Basinas3, Laura Kenny2, Padraic McGowan4, Marie Coggins5.   

Abstract

BACKGROUND: Pesticides and their potential adverse health effects are of great concern and there is a dearth of knowledge regarding occupational exposure to pesticides among amenity horticulturalists.
OBJECTIVE: This study aims to measure occupational exposures to amenity horticuturalists using pesticides containing the active ingredients, glyphosate and fluroxypyr by urinary biomonitoring.
METHODS: A total of 40 work tasks involving glyphosate and fluroxypyr were surveyed over the period of June - October 2015. Workers used a variety of pesticide application methods; manual knapsack sprayers, controlled droplet applicators, pressurised lance applicators and boom sprayers. Pesticide concentrations were measured in urine samples collected pre and post work tasks using liquid chromatography tandem mass spectrometry (LC-MS/MS). Differences in pesticide urinary concentrations pre and post work task, and across applications methods were analysed using paired t-tests and linear regression.
RESULTS: Pesticide urinary concentrations were higher than those reported for environmental exposures and comparable to those reported in some agricultural studies. Log-transformed pesticide concentrations were statistically significantly higher in post-work samples compared to those in pre-work samples (paired t-test, p<0.001; for both μgL-1 and μmol/mol creatinine). Urinary pesticide concentrations in post-work samples had a geometric mean (geometric standard deviation) of 0.66 (1.11) μgL-1 for glyphosate and 0.29 (1.69) μgL-1 for fluroxypyr. Linear regression revealed a statistically significant positive association to exist between the time-interval between samples and the log-transformed adjusted (i.e. post- minus pre-task) pesticide urinary concentrations (β=0.0039; p<0.0001).
CONCLUSION: Amenity horticulturists can be exposed to pesticides during tasks involving these products. Further research is required to evaluate routes of exposure among this occupational group. Crown
Copyright © 2017. Published by Elsevier GmbH. All rights reserved.

Entities:  

Keywords:  Biomonitoring; Fluroxypyr; Fluroxypyr (Pubmed CID: 50465); Glyphosate; Glyphosate (Pubmed CID: 3496); Occupational exposure; Pesticides; Urine

Mesh:

Substances:

Year:  2017        PMID: 28668341     DOI: 10.1016/j.ijheh.2017.06.008

Source DB:  PubMed          Journal:  Int J Hyg Environ Health        ISSN: 1438-4639            Impact factor:   5.840


  7 in total

1.  Effects of exposure to glyphosate on oxidative stress, inflammation, and lung function in maize farmers, Northern Thailand.

Authors:  Sutthinee Sidthilaw; Ratana Sapbamrer; Chaicharn Pothirat; Klintean Wunnapuk; Supakit Khacha-Ananda
Journal:  BMC Public Health       Date:  2022-07-14       Impact factor: 4.135

2.  A Method for the Analysis of Glyphosate, Aminomethylphosphonic Acid, and Glufosinate in Human Urine Using Liquid Chromatography-Tandem Mass Spectrometry.

Authors:  Zhong-Min Li; Kurunthachalam Kannan
Journal:  Int J Environ Res Public Health       Date:  2022-04-19       Impact factor: 4.614

3.  Analysis of glyphosate, aminomethylphosphonic acid, and glufosinate from human urine by HRAM LC-MS.

Authors:  Adrian A Franke; Xingnan Li; Jennifer F Lai
Journal:  Anal Bioanal Chem       Date:  2020-10-03       Impact factor: 4.142

4.  Concentration Distribution and Analysis of Urinary Glyphosate and Its Metabolites in Occupationally Exposed Workers in Eastern China.

Authors:  Feng Zhang; Yanqiong Xu; Xin Liu; Liping Pan; Enmin Ding; Jianrui Dou; Baoli Zhu
Journal:  Int J Environ Res Public Health       Date:  2020-04-24       Impact factor: 3.390

5.  Glyphosate toxicity and carcinogenicity.

Authors:  Tomoyuki Kawada
Journal:  EXCLI J       Date:  2018-08-16       Impact factor: 4.068

Review 6.  The evidence of human exposure to glyphosate: a review.

Authors:  Christina Gillezeau; Maaike van Gerwen; Rachel M Shaffer; Iemaan Rana; Luoping Zhang; Lianne Sheppard; Emanuela Taioli
Journal:  Environ Health       Date:  2019-01-07       Impact factor: 5.984

7.  Quantifiable urine glyphosate levels detected in 99% of the French population, with higher values in men, in younger people, and in farmers.

Authors:  Daniel Grau; Nicole Grau; Quentin Gascuel; Christian Paroissin; Cécile Stratonovitch; Denis Lairon; Damien A Devault; Julie Di Cristofaro
Journal:  Environ Sci Pollut Res Int       Date:  2022-01-12       Impact factor: 5.190

  7 in total

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