Literature DB >> 2866768

Effect of diamide on proton translocation by the mitochondrial H+-ATPase.

F Zanotti, F Guerrieri, R Scarfò, J Berden, S Papa.   

Abstract

Treatment of sonic submitochondrial particles with the bifunctional thiol reagent, diamide, results in an enhancement of proton conductivity and ATPase activity, which is reversed by the reducing agent dithiothreitol, is suppressed by Fo inhibitors like oligomycin and is absent in particles that are deprived of peripheral Fo polypeptides. The effect of diamide is apparently due to oxidation of dithiols to disulfides in peripheral polypeptide(s) of Fo.

Entities:  

Mesh:

Substances:

Year:  1985        PMID: 2866768     DOI: 10.1016/0006-291x(85)91904-7

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN: 0006-291X            Impact factor:   3.575


  3 in total

Review 1.  The structural and functional connection between the catalytic and proton translocating sectors of the mitochondrial F1F0-ATP synthase.

Authors:  S Papa; F Zanotti; A Gaballo
Journal:  J Bioenerg Biomembr       Date:  2000-08       Impact factor: 2.945

Review 2.  Bacterial adenosine 5'-triphosphate synthase (F1F0): purification and reconstitution of F0 complexes and biochemical and functional characterization of their subunits.

Authors:  E Schneider; K Altendorf
Journal:  Microbiol Rev       Date:  1987-12

3.  Regulation of vascular smooth muscle cell bioenergetic function by protein glutathiolation.

Authors:  Bradford G Hill; Ashlee N Higdon; Brian P Dranka; Victor M Darley-Usmar
Journal:  Biochim Biophys Acta       Date:  2009-11-24
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.