Literature DB >> 28666544

Advances in Alzheimer's Diagnosis and Therapy: The Implications of Nanotechnology.

Mohammad Javad Hajipour1, Michelle R Santoso2, Farhad Rezaee3, Haniyeh Aghaverdi4, Morteza Mahmoudi5, George Perry6.   

Abstract

Alzheimer's disease (AD) is a type of dementia that causes major issues for patients' memory, thinking, and behavior. Despite efforts to advance AD diagnostic and therapeutic tools, AD remains incurable due to its complex and multifactorial nature and lack of effective diagnostics/therapeutics. Nanoparticles (NPs) have demonstrated the potential to overcome the challenges and limitations associated with traditional diagnostics/therapeutics. Nanotechnology is now offering new tools and insights to advance our understanding of AD and eventually may offer new hope to AD patients. Here, we review the key roles of nanotechnologies in the recent literature, in both diagnostic and therapeutic aspects of AD, and discuss how these achievements may improve patient prognosis and quality of life.
Copyright © 2017 Elsevier Ltd. All rights reserved.

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Year:  2017        PMID: 28666544     DOI: 10.1016/j.tibtech.2017.06.002

Source DB:  PubMed          Journal:  Trends Biotechnol        ISSN: 0167-7799            Impact factor:   19.536


  24 in total

Review 1.  Leveraging the interplay of nanotechnology and neuroscience: Designing new avenues for treating central nervous system disorders.

Authors:  Elizabeth S Smith; Joshua E Porterfield; Rangaramanujam M Kannan
Journal:  Adv Drug Deliv Rev       Date:  2019-03-04       Impact factor: 15.470

2.  A field-deployable diagnostic assay for the visual detection of misfolded prions.

Authors:  Peter R Christenson; Manci Li; Gage Rowden; Marc D Schwabenlander; Tiffany M Wolf; Sang-Hyun Oh; Peter A Larsen
Journal:  Sci Rep       Date:  2022-07-18       Impact factor: 4.996

3.  Biosynthesis of AgNPs by B. maydis and its antifungal effect against Exserohilum turcicum.

Authors:  Weidong Huang; Xueliang Fang; Hongdao Wang; Fengchan Chen; Haiming Duan; Yaling Bi; Haibing Yu
Journal:  IET Nanobiotechnol       Date:  2018-08       Impact factor: 1.847

4.  Development of a Label-Free Immunosensor for Clusterin Detection as an Alzheimer's Biomarker.

Authors:  Kamrul Islam; Samar Damiati; Jagriti Sethi; Ahmed Suhail; Genhua Pan
Journal:  Sensors (Basel)       Date:  2018-01-20       Impact factor: 3.576

Review 5.  Use of Peptides for the Management of Alzheimer's Disease: Diagnosis and Inhibition.

Authors:  Mohammad H Baig; Khurshid Ahmad; Gulam Rabbani; Inho Choi
Journal:  Front Aging Neurosci       Date:  2018-02-07       Impact factor: 5.750

Review 6.  Implications of PI3K/AKT/PTEN Signaling on Superoxide Dismutases Expression and in the Pathogenesis of Alzheimer's Disease.

Authors:  Satoru Matsuda; Yukie Nakagawa; Ai Tsuji; Yasuko Kitagishi; Atsuko Nakanishi; Toshiyuki Murai
Journal:  Diseases       Date:  2018-04-20

Review 7.  DNA Microsystems for Biodiagnosis.

Authors:  Alana Torres Vidal; Igor L Medintz; Hieu Bui
Journal:  Micromachines (Basel)       Date:  2020-04-23       Impact factor: 2.891

8.  The Interplay of Tau Protein and β-Amyloid: While Tauopathy Spreads More Profoundly Than Amyloidopathy, Both Processes Are Almost Equally Pathogenic.

Authors:  Mahsa Pourhamzeh; Mohammad Taghi Joghataei; Soraya Mehrabi; Reza Ahadi; Seyed Mohammad Massood Hojjati; Nasrin Fazli; Seyed Massood Nabavi; Hossein Pakdaman; Koorosh Shahpasand
Journal:  Cell Mol Neurobiol       Date:  2020-07-22       Impact factor: 5.046

Review 9.  Oxidant/Antioxidant Imbalance in Alzheimer's Disease: Therapeutic and Diagnostic Prospects.

Authors:  Joanna Wojsiat; Katarzyna Marta Zoltowska; Katarzyna Laskowska-Kaszub; Urszula Wojda
Journal:  Oxid Med Cell Longev       Date:  2018-01-31       Impact factor: 6.543

10.  The hot sites of α-synuclein in amyloid fibril formation.

Authors:  Anahita Khammari; Seyed Shahriar Arab; Mohammad Reza Ejtehadi
Journal:  Sci Rep       Date:  2020-07-22       Impact factor: 4.379

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