J Geurts1, A Hohnen1, T Vranken1, P Moh2. 1. Department of Orthopaedic Surgery, CAPHRI School of Public Health and Primary Care, Maastricht University, Maastricht, The Netherlands. 2. St.John of God Hospital, Duayaw Nkwanta, Ghana.
Abstract
OBJECTIVES: To identify a standard treatment regime or highly successful procedure for chronic osteomyelitis in low- and middle-income countries. METHODS: Systematic review following PRISMA guidelines. RESULTS: The initial search resulted in 102 studies of which nine met the inclusion criteria and were analysed qualitatively. The included studies involved 1173 patients from Africa and Asia. All patients were diagnosed with chronic osteomyelitis. Surgical and antibiotic treatment regimens differed substantially. No better judgement than moderate risk of selection bias could be made due to the study designs. CONCLUSIONS: The evidence is not sufficiently robust to identify the most effective treatment, or to even allow a recommendation of the best suitable treatment of chronic osteomyelitis in low-income countries.
OBJECTIVES: To identify a standard treatment regime or highly successful procedure for chronic osteomyelitis in low- and middle-income countries. METHODS: Systematic review following PRISMA guidelines. RESULTS: The initial search resulted in 102 studies of which nine met the inclusion criteria and were analysed qualitatively. The included studies involved 1173 patients from Africa and Asia. All patients were diagnosed with chronic osteomyelitis. Surgical and antibiotic treatment regimens differed substantially. No better judgement than moderate risk of selection bias could be made due to the study designs. CONCLUSIONS: The evidence is not sufficiently robust to identify the most effective treatment, or to even allow a recommendation of the best suitable treatment of chronic osteomyelitis in low-income countries.
Keywords:
Ghana; Ghana ; chronic osteomyelitis; low- and middle-income country; osteomielitis crónica; ostéomyélite chronique; pays à revenu faible et intermédiaire; países con ingresos bajos y medios; review; revisión; revue
Authors: Elizabeth K Tissingh; Leonard Marais; Antonio Loro; Deepa Bose; Nilo T Paner; Jamie Ferguson; Mario Morgensten; Martin McNally Journal: EFORT Open Rev Date: 2022-05-31
Authors: Mario Morgenstern; Christoph Erichsen; Matthias Militz; Zhao Xie; Jiachen Peng; James Stannard; Willem-Jan Metsemakers; Dirk Schaefer; Volker Alt; Kjeld Søballe; Michael Nerlich; Richard E Buckley; Michael Blauth; Michael Suk; Frankie Leung; Jorge D Barla; Kiminori Yukata; Bi Qing; Stephen L Kates Journal: J Orthop Res Date: 2020-07-27 Impact factor: 3.102