Literature DB >> 28665444

Prevalence of sarcopenia and its association with dysphagia in cancer patients who require rehabilitation.

Hidetaka Wakabayashi1, Rimiko Takahashi, Naoko Watanabe, Hideyuki Oritsu, Yoshitaka Shimizu.   

Abstract

OBJECTIVE: To assess the prevalence of sarcopaenia and the association between sarcopaenia, activities of daily living, and dysphagia in cancer patients who require rehabilitation.
METHODS: A cross-sectional study was performed in 83 consecutive cancer patients referred to the Department of Rehabilitation Medicine. Skeletal muscle index was calculated as total psoas muscle area assessed via abdominal computed tomography divided by height squared. Sarcopaenia was diagnosed using the Asian Working Group for Sarcopenia criteria. Activities of daily living were evaluated with the Barthel Index. Dysphagia was assessed with the 10-item Eating Assessment Tool (EAT-10).
RESULTS: Study participants were 50 males and 33 females (mean age 71, standard deviation 12 years). Sarcopaenia was observed in 66 (80%) patients. The median Barthel Index score was 55 (interquartile range: 25-75). Thirty-five (42%) patients were diagnosed as having dysphagia. Logistic regression analysis of dysphagia adjusted for sarcopaenia, Barthel Index score, age, and reason for hospitalization showed that sarcopaenia (odds ratio (OR) 3.616; 95% confidence interval (95% CI) 0.926-14.114; p = 0.064) and Barthel Index score (OR 0.984; 95% CI 0.966-1.002; p = 0.073) did not reach statistical significance.
CONCLUSION: The prevalence of sarcopaenia in cancer patients who require rehabilitation is very high. The power of this study was too low to observe a significant association between sarcopaenia and dysphagia.

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Year:  2017        PMID: 28665444     DOI: 10.2340/16501977-2253

Source DB:  PubMed          Journal:  J Rehabil Med        ISSN: 1650-1977            Impact factor:   2.912


  5 in total

1.  Disease-specific Nutritional Physical Therapy: A Position Paper by the Japanese Association of Rehabilitation Nutrition (Secondary Publication).

Authors:  Tatsuro Inoue; Izumi Takeuchi; Yuki Iida; Kohei Takahashi; Fumihiko Nagano; Shinjiro Miyazaki; Kengo Shirado; Yoshihiro Yoshimura; Ryo Momosaki; Keisuke Maeda; Hidetaka Wakabayashi
Journal:  JMA J       Date:  2022-03-25

Review 2.  Systematic Review and Meta-Analysis of the Association between Sarcopenia and Dysphagia.

Authors:  W-T Zhao; M Yang; H-M Wu; L Yang; X-M Zhang; Y Huang
Journal:  J Nutr Health Aging       Date:  2018       Impact factor: 4.075

Review 3.  Sarcopenic Dysphagia: A Narrative Review from Diagnosis to Intervention.

Authors:  Kuan-Cheng Chen; Ying Jeng; Wei-Ting Wu; Tyng-Guey Wang; Der-Sheng Han; Levent Özçakar; Ke-Vin Chang
Journal:  Nutrients       Date:  2021-11-12       Impact factor: 5.717

Review 4.  Molecular and Neural Mechanism of Dysphagia Due to Cancer.

Authors:  Ikuko Okuni; Yuta Otsubo; Satoru Ebihara
Journal:  Int J Mol Sci       Date:  2021-06-29       Impact factor: 5.923

5.  Dose Finding and Food Effect Studies of a Novel Abiraterone Acetate Formulation for Oral Suspension in Comparison to a Reference Formulation in Healthy Male Subjects.

Authors:  Tamás Jordán; Orsolya Basa-Dénes; Réka Angi; János Orosz; Zsolt Ötvös; Andrea Ujhelyi; Genovéva Filipcsei; László Molnár; Tamás Solymosi; Hristos Glavinas; Dominic Capone; Nicola Whitfield; John McDermott; Litza McKenzie; Lauren Shurety; Elizabeth Manning Duus
Journal:  Pharmaceutics       Date:  2021-12-16       Impact factor: 6.321

  5 in total

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