Justin S Golub1. 1. Department of Otolaryngology - Head and Neck Surgery, Columbia University College of Physicians and Surgeons, NewYork-Presbyterian/Columbia University Medical Center, New York, New York, USA.
Abstract
PURPOSE OF REVIEW: To discuss brain changes associated with age-related hearing loss (ARHL), including cognitive abilities and neuroimaging findings. This information will be helpful to hypothesize and ultimately understand how ARHL may be mechanistically related to changes in brain structure and function. It will also be helpful to guide the strength of treatment recommendations. RECENT FINDINGS: ARHL has recently been associated with cognitive impairment and dementia. This observation is present in both cross-sectional and longitudinal analyses, in diverse patient populations, and after controlling for a variety of potential confounders. Preliminary brain imaging studies show smaller brain volumes as well as white matter tract dysfunction in adults with hearing loss. SUMMARY: ARHL is related to cognitive impairment and dementia. More study is needed to determine if the association is causal, and if treatment efforts could reduce the risk of cognitive impairment and dementia. Given the low risk of treating ARHL and the potential health benefit for the aging brain, it is recommended to proactively discuss ARHL and treatment with patients.
PURPOSE OF REVIEW: To discuss brain changes associated with age-related hearing loss (ARHL), including cognitive abilities and neuroimaging findings. This information will be helpful to hypothesize and ultimately understand how ARHL may be mechanistically related to changes in brain structure and function. It will also be helpful to guide the strength of treatment recommendations. RECENT FINDINGS: ARHL has recently been associated with cognitive impairment and dementia. This observation is present in both cross-sectional and longitudinal analyses, in diverse patient populations, and after controlling for a variety of potential confounders. Preliminary brain imaging studies show smaller brain volumes as well as white matter tract dysfunction in adults with hearing loss. SUMMARY: ARHL is related to cognitive impairment and dementia. More study is needed to determine if the association is causal, and if treatment efforts could reduce the risk of cognitive impairment and dementia. Given the low risk of treating ARHL and the potential health benefit for the aging brain, it is recommended to proactively discuss ARHL and treatment with patients.
Authors: Sara Ponticorvo; Renzo Manara; Josef Pfeuffer; Arianna Cappiello; Sofia Cuoco; Maria Teresa Pellecchia; Renato Saponiero; Donato Troisi; Claudia Cassandro; Marta John; Alfonso Scarpa; Ettore Cassandro; Francesco Di Salle; Fabrizio Esposito Journal: Hum Brain Mapp Date: 2019-02-04 Impact factor: 5.038
Authors: Justin S Golub; Katharine K Brewster; Adam M Brickman; Adam J Ciarleglio; Ana H Kim; José A Luchsinger; Bret R Rutherford Journal: JAMA Otolaryngol Head Neck Surg Date: 2019-02-01 Impact factor: 6.223
Authors: Alexandria L Irace; Brady Q Rippon; Adam M Brickman; José A Luchsinger; Justin S Golub Journal: Otol Neurotol Date: 2022-03-01 Impact factor: 2.311
Authors: Justin S Golub; Katharine K Brewster; Adam M Brickman; Adam J Ciarleglio; Ana H Kim; José A Luchsinger; Bret R Rutherford Journal: Am J Geriatr Psychiatry Date: 2020-01-21 Impact factor: 4.105