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Literature DB >> 2866091

Structure of the murine Thy-1 gene.

Abstract

We have cloned the murine Thy-1.1 (AKR) and Thy-1.2 (Balb/c) genes. The complete exon/intron structure and the nucleotide sequence of the Thy-1.2 gene was determined. The gene contains four exons and three intervening sequences. The complete transcriptional unit gives rise to a tissue and developmental stage-specific mRNA of 1850 bp. The 5' end of the gene has multiple initiation sites and a non-TATA box promoter. The 3' end shows a single polyadenylation site after a very long untranslated region.

Entities: Chemical

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Year: 1985 PMID： 2866091 PMCID： PMC554456 DOI： 10.1002/j.1460-2075.1985.tb03886.x

Source DB: PubMed Journal: EMBO J ISSN： 0261-4189 Impact factor: 11.598

44 in total

10. Anti-Thy-1 antibody responses evoked by Thy-1 antigen expressed in transfected mouse mastocytoma cells and rat fibroblast.

Authors: K Isobe; A Fortunato; V Giguere; F Grosveld; N A Mitchison
Journal: Immunology Date: 1985-11 Impact factor: 7.397

Structure of the murine Thy-1 gene.

1. Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids.

2. 3'-Terminal addition to HeLa cell nuclear and cytoplasmic poly (A).

3. Hybrid cell lines with T-cell characteristics.

4. Location of the gene for Theta antigen in the mouse.

5. Ribonucleic acid isolated by cesium chloride centrifugation.

6. A transplantable myelomonocytic leukemia in BALB-c mice: cytology, karyotype, and muramidase content.

7. Lambdoid phages that simplify the recovery of in vitro recombinants.

8. The postnatal development of antigens on mouse brain cell surfaces.

9. Rat insulin genes: construction of plasmids containing the coding sequences.

10. THE AKR THYMIC ANTIGEN AND ITS DISTRIBUTION IN LEUKEMIAS AND NERVOUS TISSUES.

1. Fc gamma receptors: gene structure and receptor function.

2. Regulation of c-fos and c-jun expression in the rat supraoptic nucleus.

3. High frequency of genetic recombination is a common feature of primate lentivirus replication.

4. Transcriptional and translational analysis of the human theta globin gene.

5. Characterization of the human N-CAM promoter.

6. Molecular cloning of the gene coding for the human T cell differentiation antigen CD7.

Review 7. Roles and regulation of Thy-1, a context-dependent modulator of cell phenotype.

8. Mouse brain CD4 transcripts encode only the COOH-terminal half of the protein.

9. Olfactory marker protein gene: its structure and olfactory neuron-specific expression in transgenic mice.

10. Anti-Thy-1 antibody responses evoked by Thy-1 antigen expressed in transfected mouse mastocytoma cells and rat fibroblast.