Literature DB >> 28658892

Poorly Differentiated Sertoli-Leydig Cell Tumour of Ovary with Heterologous Elements.

Tapan Kumar Sahoo1, Tushar Kar2, Asaranti Kar3, Sasmita Panda4.   

Abstract

Sertoli-Leydig Cell Tumour (SLCT) is included under sex-cord stromal tumour of testis or ovary. Ovarian pathology is an extremely rare entity constituting less than 0.5% of all ovarian neoplasms. Majority of the cases present at younger age group, i.e., 2nd and 3rd decade of life. The clinical presentation depends on either mass effect or excess hormone production. Virillization symptoms are the most common presentation and depend upon the quantity of androgen production. Most of the patients have a unilateral mass without extraovarian spread and present at stage-I. Treatment and prognosis depends on the degree of the differentiation and the stage of the disease. Here, we report a case of SLCT of the ovary in a young female. The patient initially presented with pain abdomen due to mass effect and was treated with conservative surgery followed by adjuvant chemotherapy due to the presence of poorly differentiated pathology with heterologous elements.

Entities:  

Keywords:  Chemotherapy; Conservative surgery; Diagnosis; Sex-cord stromal tumour

Year:  2017        PMID: 28658892      PMCID: PMC5483794          DOI: 10.7860/JCDR/2017/25262.9860

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  9 in total

1.  A case of poorly differentiated Sertoli-Leydig tumor of the ovary.

Authors:  Eduardo Lara-Torre; Jennifer E Dietrich; Alan Kaplan; Henry Lopez; Ian Jaffee
Journal:  J Pediatr Adolesc Gynecol       Date:  2004-02       Impact factor: 1.814

2.  Ovarian Sertoli-Leydig cell tumors. a retrospective MITO study.

Authors:  Cristina Sigismondi; Angiolo Gadducci; Domenica Lorusso; Massimo Candiani; Enrico Breda; Francesco Raspagliesi; Gennaro Cormio; Marco Marinaccio; Giorgia Mangili
Journal:  Gynecol Oncol       Date:  2012-03-22       Impact factor: 5.482

3.  Sertoli-Leydig cell tumors of the ovary: a Taiwanese Gynecologic Oncology Group study.

Authors:  Chia-Sui Weng; Min-Yu Chen; Tao-Yeuan Wang; Hsiao-Wen Tsai; Yao-Ching Hung; Ken-Jen Yu; Ying-Cheng Chiang; Hao Lin; Chien-Hsing Lu; Hung-Hsueh Chou
Journal:  Taiwan J Obstet Gynecol       Date:  2013-03       Impact factor: 1.705

4.  Sertoli-Leydig cell tumor: a rare ovarian neoplasm. Case report and review of literature.

Authors:  Poonam Sachdeva; Raksha Arora; Chandan Dubey; Astha Sukhija; Mridula Daga; Deepak Kumar Singh
Journal:  Gynecol Endocrinol       Date:  2008-04       Impact factor: 2.260

Review 5.  Immunohistochemistry as a diagnostic aid in the evaluation of ovarian tumors.

Authors:  W Glenn McCluggage; Robert H Young
Journal:  Semin Diagn Pathol       Date:  2005-02       Impact factor: 3.464

6.  Sertoli Leydig cell tumor with heterologous gastrointestinal epithelium: a case report.

Authors:  Sandeep R Mathur; Neerja Bhatla; I Satish Rao; Manoj K Singh
Journal:  Indian J Pathol Microbiol       Date:  2003-01       Impact factor: 0.740

Review 7.  Ovarian Sertoli-Leydig cell tumors. A clinicopathological analysis of 207 cases.

Authors:  R H Young; R E Scully
Journal:  Am J Surg Pathol       Date:  1985-08       Impact factor: 6.394

8.  A clinicopathological analysis of 40 cases of ovarian Sertoli-Leydig cell tumors.

Authors:  Ting Gui; Dongyan Cao; Keng Shen; Jiaxin Yang; Yiwen Zhang; Qi Yu; Xirun Wan; Yang Xiang; Yu Xiao; Lina Guo
Journal:  Gynecol Oncol       Date:  2012-07-28       Impact factor: 5.482

9.  Poorly differentiated ovarian sertoli-leydig cell tumor in a 16-year-old single woman: a case report and literature review.

Authors:  Ahmed Abu-Zaid; Ayman Azzam; Lama Abdulhamid Alghuneim; Mona Tarek Metawee; Tarek Amin; Turki Omar Al-Hussain
Journal:  Case Rep Obstet Gynecol       Date:  2013-06-25
  9 in total

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