Literature DB >> 28658838

Hemi-Chorea in a Patient with Ketotic Hyperglycemia: An Unusual Presentation.

Pendela Venkata Satish1, Kudaravalli Pujitha2, Neha Agrawal1, Thomas Mathew1, Sudha Vidyasagar3.   

Abstract

Chorea has often been associated with lesions in the basal ganglia and in the sub thalamic nucleus. It is possible for a patient with chorea-ballismus to have hyperglycemia at the initial presentation. We hereby present a case of an 81-year-old female, who was on treatment for type 2 diabetes mellitus and presented to us with sub acute onset of abnormal movements of right side of the body. She had semi purposeful, rapid and jerky movements of right upper limb and lower limb along with abnormal tongue movements. Laboratory data showed very high blood glucose levels, urine ketones were positive and pH of arterial blood was normal. MRI brain showed hyperintensities in right basal ganglia. So, hyperglycemia induced hemichorea was considered as a possibility and she was treated with insulin. These abnormal movements decreased subsequently with treatment and patient is doing better in the follow-up visits. This presentation is extremely rare, as review of literature showed similar presentations in patients with non ketotic hyperglycemia but not reported so far in diabetic ketosis.

Entities:  

Keywords:  Choreo-athetoid movements; Diabetic ketosis; Type 2 diabetes mellitus

Year:  2017        PMID: 28658838      PMCID: PMC5483740          DOI: 10.7860/JCDR/2017/27266.9939

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  10 in total

1.  Chorea-ballism associated with nonketotic hyperglycaemia or diabetic ketoacidosis: characteristics of 25 patients in Korea.

Authors:  Seung-Hwan Lee; Jeong-Ah Shin; Ji-Hyun Kim; Jang-Won Son; Kang-Woo Lee; Seung-Hyun Ko; Seung-Ho Yang; Byung Chul Son; Yu-Bae Ahn
Journal:  Diabetes Res Clin Pract       Date:  2011-05-31       Impact factor: 5.602

2.  Hyperosmolar non-ketotic hyperglycaemia: an important and reversible cause of acute bilateral ballismus.

Authors:  Philip Milburn-McNulty; Benedict D Michael; Henry J Woodford; Andrew Nicolson
Journal:  BMJ Case Rep       Date:  2012-06-21

3.  Hemichorea-hemiballism as the first presentation of type 2 diabetes mellitus.

Authors:  Andre C Felicio; Claudia V Chang; Clecio Godeiro-Junior; Marina P Okoshi; Henrique B Ferraz
Journal:  Arq Neuropsiquiatr       Date:  2008-06       Impact factor: 1.420

Review 4.  Transient hemichorea/hemiballismus associated with new onset hyperglycemia.

Authors:  G Ifergane; R Masalha; Y O Herishanu
Journal:  Can J Neurol Sci       Date:  2001-11       Impact factor: 2.104

5.  [A case of hemichorea with hyperglycemia presenting with low signal intensity in the striatum on T2*-weighted gradient-echo magnetic resonance imaging].

Authors:  Yutaka Suto; Masatada Mori; Hiroshi Kagimoto; Jun Saito
Journal:  Rinsho Shinkeigaku       Date:  2004-02

6.  Chorea-ballism as a manifestation of decompensated type 2 diabetes mellitus.

Authors:  Claudia Veiga Chang; Andre Carvalho Felicio; Clecio de Oliveira Godeiro; Luiz Shiguero Matsubara; Daniela Rezende Duarte; Henrique Ballalai Ferraz; Marina Politi Okoshi
Journal:  Am J Med Sci       Date:  2007-03       Impact factor: 2.378

7.  Hemichorea-hemiballism: an explanation for MR signal changes.

Authors:  D E Shan; D M Ho; C Chang; H C Pan; M M Teng
Journal:  AJNR Am J Neuroradiol       Date:  1998-05       Impact factor: 3.825

8.  Regional cerebral blood flow decreases during hyperglycemia.

Authors:  R B Duckrow; D C Beard; R W Brennan
Journal:  Ann Neurol       Date:  1985-03       Impact factor: 10.422

9.  Nonketotic hyperglycemia appearing as choreoathetosis or ballism.

Authors:  W G Rector; H F Herlong; H Moses
Journal:  Arch Intern Med       Date:  1982-01

10.  Hyperintense putamen on T1-weighted MR images in a case of chorea with hyperglycemia.

Authors:  C Nagai; T Kato; T Katagiri; H Sasaki
Journal:  AJNR Am J Neuroradiol       Date:  1995 Jun-Jul       Impact factor: 3.825

  10 in total
  1 in total

Review 1.  One Side of the Story; Clues to Etiology in Patients with Asymmetric Chorea.

Authors:  Molly Cincotta; Ruth H Walker
Journal:  Tremor Other Hyperkinet Mov (N Y)       Date:  2022-01-31
  1 in total

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