Literature DB >> 28658784

An Extremely Rare Case of Small Cell Carcinoma in Submandibular Salivary Gland.

Nigi Ross Philip1, Teerthanath Srinivas2, Ruhisalma Naagar1, Venkatesh Srinivas3.   

Abstract

Small Cell Carcinoma (SCC) of the salivary gland is a rare and aggressive tumour accounting for about less than 1% of the salivary gland tumours. Submandibular gland involvement is extremely rare. These tumours frequently present with metastasis to lymph node and distant organs. We report a case of a 30-year-old male patient who presented with a swelling on the left side of the face below the jaw and the floor of the mouth. The tumour was excised followed by histopathological evaluation and diagnosed as SCC of left submandibular gland. Immunohistochemistry was positive for pan cytokeratin, synaptophysin, chromogranin, Ki-67, CK5/6, and negative for Thyroid Transcription Factor (TTF-1) which confirmed that the tumour was SCC of submandibular salivary gland.

Entities:  

Keywords:  Chromogranin; Pan cytokeratin; Synaptophysin

Year:  2017        PMID: 28658784      PMCID: PMC5483686          DOI: 10.7860/JCDR/2017/22341.9885

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  5 in total

Review 1.  Small-cell undifferentiated carcinoma of the submandibular gland: an extremely rare extrapulmonary site.

Authors:  Yen-Chun Lin; Hung-Pin Wu; Jeh-En Tzeng
Journal:  Am J Otolaryngol       Date:  2005 Jan-Feb       Impact factor: 1.808

2.  Small cell carcinoma of the submandibular gland: a rare small round blue cell tumor.

Authors:  David M Walters; Stewart C Little; Richard B Hessler; Christine G Gourin
Journal:  Am J Otolaryngol       Date:  2007 Mar-Apr       Impact factor: 1.808

Review 3.  Small cell carcinoma of the salivary gland: a systematic literature review and two case reports.

Authors:  J P S Servato; S J da Silva; P R de Faria; S V Cardoso; A M Loyola
Journal:  Int J Oral Maxillofac Surg       Date:  2012-11-03       Impact factor: 2.789

4.  Parotid small cell carcinoma presenting with long-term survival after surgery alone: a case report.

Authors:  Takeharu Kanazawa; Noriyoshi Fukushima; Hidetaka Tanaka; Juntaro Shiba; Hiroshi Nishino; Hiroyuki Mineta; Keiichi Ichimura
Journal:  J Med Case Rep       Date:  2012-12-28

5.  Primary neuroendocrine small cell carcinoma of the parotid gland: A case report and review of the literature.

Authors:  Minda Liu; Ming Zhong; Changfu Sun
Journal:  Oncol Lett       Date:  2014-06-17       Impact factor: 2.967

  5 in total
  1 in total

1.  Metastatic small cell neuroendocrine carcinoma of the submandibular gland from the lung: A case report.

Authors:  Dong Hoon Lee; Jo Heon Kim; Tae Mi Yoon; Joon Kyoo Lee; Sang Chul Lim
Journal:  Medicine (Baltimore)       Date:  2020-01       Impact factor: 1.817

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.