Deepak Kumar1, Padmapriya Kasukurti2, Srinivasa Murthy3. 1. Associate Professor, Department of Pathology, ESIC Medical College and PGIMSR, Bangalore, Karnataka, India. 2. Assistant Professor, Department of Pathology, Sapthagiri Institute of Medical Sciences and Research Centre, Bangalore, Karnataka, India. 3. Professor and Head, Department of Pathology, ESIC Medical College and PGIMSR, Bangalore, Karnataka, India.
Abstract
INTRODUCTION: Erythrocytes and platelets share an intimate development history, due to which special interest is centered on their relationship. Mature Red Blood Cells (RBCs) and platelets show a similar physiological rhythm, and are concurrently involved in numerous pathologic states. AIM: To identify subtle relationships between various RBC and platelet parameters with an objective to analyse if a linear correlation co-exists between and among them in physiological/pathological states. MATERIALS AND METHODS: A prospective analysis of 1250 EDTA blood samples was conducted. The five RBC parameters (RBC count, HCT, MCV, RDW, Hb) and four platelet parameters (platelet count, PCT, MPV, PDW) obtained from each case were statistically analysed for linear dependence. RESULTS: A statistically significant direct linear relationship was found between RDW with platelet count and PCT. A statistically significant inverse linear relationship was noticed between the following parameters: i) HCT with platelet count and PCT; ii) MCV with platelet count and PCT; iii) Haemoglobin and platelet count. CONCLUSION: A linear correlation, either direct or inverse, was seen among various parallel RBC and platelet parameters.
INTRODUCTION: Erythrocytes and platelets share an intimate development history, due to which special interest is centered on their relationship. Mature Red Blood Cells (RBCs) and platelets show a similar physiological rhythm, and are concurrently involved in numerous pathologic states. AIM: To identify subtle relationships between various RBC and platelet parameters with an objective to analyse if a linear correlation co-exists between and among them in physiological/pathological states. MATERIALS AND METHODS: A prospective analysis of 1250 EDTA blood samples was conducted. The five RBC parameters (RBC count, HCT, MCV, RDW, Hb) and four platelet parameters (platelet count, PCT, MPV, PDW) obtained from each case were statistically analysed for linear dependence. RESULTS: A statistically significant direct linear relationship was found between RDW with platelet count and PCT. A statistically significant inverse linear relationship was noticed between the following parameters: i) HCT with platelet count and PCT; ii) MCV with platelet count and PCT; iii) Haemoglobin and platelet count. CONCLUSION: A linear correlation, either direct or inverse, was seen among various parallel RBC and platelet parameters.
Entities:
Keywords:
Automation; Ontogeny; Platelet parameters; Red blood cell parameters
Authors: P J Stohlawetz; L Dzirlo; N Hergovich; E Lackner; C Mensik; H G Eichler; E Kabrna; K Geissler; B Jilma Journal: Blood Date: 2000-05-01 Impact factor: 22.113
Authors: Ramón Figueroa-Mujica; Luis Angel Ccahuantico; Maycol Suker Ccorahua-Rios; Juan José Sanchez-Huaman; Cinthya Vásquez-Velasquez; Jorge M Ponce-Huarancca; Rodrigo E Rozas-Gamarra; Gustavo F Gonzales Journal: Life (Basel) Date: 2022-05-13