Literature DB >> 2865713

Intrathecal somatostatin in terminally ill patients. A report of two cases.

J Meynadier1, J Chrubasik, M Dubar, E Wünsch.   

Abstract

Intrathecal morphine has been shown to be reliable in producing analgesia in patients with intractable cancer pain. Recently, we have demonstrated that intrathecal somatostatin is as effective in the treatment of cancer pain as intrathecal morphine. This report presents 2 cases in whom analgesia could be maintained for 60 and 25 days, respectively, under continuous intrathecal infusion of somatostatin by means of infusion devices.

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Year:  1985        PMID: 2865713     DOI: 10.1016/0304-3959(85)90224-6

Source DB:  PubMed          Journal:  Pain        ISSN: 0304-3959            Impact factor:   6.961


  7 in total

1.  Tonic control of peripheral cutaneous nociceptors by somatostatin receptors.

Authors:  S M Carlton; J Du; S Zhou; R E Coggeshall
Journal:  J Neurosci       Date:  2001-06-01       Impact factor: 6.167

Review 2.  The epidural and intrathecal administration of somatotrophin-release inhibiting factor: native and synthetic analogues.

Authors:  D P Beltrutti; S Moessinger; G Varrassi
Journal:  Curr Rev Pain       Date:  2000

3.  Effects of somatostatin on the responses of rostrally projecting spinal dorsal horn neurons to noxious stimuli in cats.

Authors:  Sung Jun Jung; Su-Hyun Jo; Sanghyuck Lee; Eunhui Oh; Min-Seok Kim; Woo Dong Nam; Seog Bae Oh
Journal:  Korean J Physiol Pharmacol       Date:  2008-10-31       Impact factor: 2.016

Review 4.  Pharmacotherapy: non-serotonergic mechanisms.

Authors:  R Spiller
Journal:  Gut       Date:  2002-07       Impact factor: 23.059

5.  [Intrathecal and epidural administration of non-opioid analgesics in acute and chronic pain treatment.].

Authors:  B Donner; M Tryba; M Zenz; M Strumpf
Journal:  Schmerz       Date:  1994-06       Impact factor: 1.107

Review 6.  Spinal drug delivery.

Authors:  T S Grabow; D Derdzinski; P S Staats
Journal:  Curr Pain Headache Rep       Date:  2001-12

7.  Treatment of patients with metastatic pancreatic and gastrointestinal tumours with the somatostatin analogue Sandostatin: a phase II study including endocrine effects.

Authors:  J G Klijn; A M Hoff; A S Planting; J Verweij; T Kok; S W Lamberts; H Portengen; J A Foekens
Journal:  Br J Cancer       Date:  1990-10       Impact factor: 7.640

  7 in total

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