C C Geelen1,2, R J E M Smeets2,3, S Schmitz2, J P van den Bergh4,5, M E J B Goossens2, J A Verbunt1,2. 1. Adelante Centre of Expertise in Rehabilitation and Audiology, Hoensbroek, The Netherlands. 2. Department of Rehabilitation Medicine, Research School CAPHRI, Maastricht University, Maastricht, The Netherlands. 3. Libra Rehabilitation and Audiology, Eindhoven, The Netherlands. 4. Department of Internal Medicine, VieCuri Medical Centre, Venlo, The Netherlands. 5. Department of Internal Medicine, Research School NUTRIM, Maastricht University, The Netherlands.
Abstract
BACKGROUND: Painful diabetic neuropathy (PDN) is known to negatively affect psychosocial functioning as expressed by enhanced levels of anxiety and depression. The aim of this study was to specify diabetes and pain-related fears. METHODS: This questionnaire-based cross-sectional study included 154 patients with PDN (mean age 65.7 ± 6.6 years). Correlation analyses corrected for age, gender, pain intensity, pain duration and insulin treatment were performed to assess the associations of fear of hypoglycaemia (Hypoglycaemia Fear Survey, HFS), kinesiophobia (Tampa Scale of Kinesiophobia, TSK), fear of pain (Pain Anxiety Symptom Scale, PASS-20), fear of falling (Falls Efficacy Scale-I, FES-I), fear of fatigue (Tampa Scale of Fatigue, TSF) and fear of negative evaluation (Brief Fear of Negative Evaluation Scale, BFNE), with quality of life (QoL) (Norfolk Quality of Life Questionnaire, Diabetic Neuropathy Version, QOL-DN) and disability (Pain Disability Index, PDI), respectively. RESULTS: In univariate analyses, all fears were independently associated with QOL-DN and PDI (p < 0.001 for all variables). Linear regression models including all fears and confounders, showed that pain intensity, pain duration and FES-I were significantly associated with QOL-DN (R2 = 0.603). Pain intensity, male gender and FES-I were significantly associated with PDI (R2 = 0.526). CONCLUSIONS: After controlling for confounders, levels of pain intensity, duration of pain and fear of falling were negatively associated with QoL in patients with PDN. Pain intensity, male gender and fear of falling were positively associated with disability. Specifying fears enables us to identify potential targets for behavioural interventions that aim to improve psychosocial well-being in patients with PDN. SIGNIFICANCE: This study shows that patients with PDN suffer from various fears, which should enable us to design a treatment strategy that directly targets these fears, hereby improving physical and psychosocial well-being in these patients.
BACKGROUND:Painful diabetic neuropathy (PDN) is known to negatively affect psychosocial functioning as expressed by enhanced levels of anxiety and depression. The aim of this study was to specify diabetes and pain-related fears. METHODS: This questionnaire-based cross-sectional study included 154 patients with PDN (mean age 65.7 ± 6.6 years). Correlation analyses corrected for age, gender, pain intensity, pain duration and insulin treatment were performed to assess the associations of fear of hypoglycaemia (Hypoglycaemia Fear Survey, HFS), kinesiophobia (Tampa Scale of Kinesiophobia, TSK), fear of pain (Pain Anxiety Symptom Scale, PASS-20), fear of falling (Falls Efficacy Scale-I, FES-I), fear of fatigue (Tampa Scale of Fatigue, TSF) and fear of negative evaluation (Brief Fear of Negative Evaluation Scale, BFNE), with quality of life (QoL) (Norfolk Quality of Life Questionnaire, Diabetic Neuropathy Version, QOL-DN) and disability (Pain Disability Index, PDI), respectively. RESULTS: In univariate analyses, all fears were independently associated with QOL-DN and PDI (p < 0.001 for all variables). Linear regression models including all fears and confounders, showed that pain intensity, pain duration and FES-I were significantly associated with QOL-DN (R2 = 0.603). Pain intensity, male gender and FES-I were significantly associated with PDI (R2 = 0.526). CONCLUSIONS: After controlling for confounders, levels of pain intensity, duration of pain and fear of falling were negatively associated with QoL in patients with PDN. Pain intensity, male gender and fear of falling were positively associated with disability. Specifying fears enables us to identify potential targets for behavioural interventions that aim to improve psychosocial well-being in patients with PDN. SIGNIFICANCE: This study shows that patients with PDN suffer from various fears, which should enable us to design a treatment strategy that directly targets these fears, hereby improving physical and psychosocial well-being in these patients.
Authors: Whitney Scott; Maite Garcia Calderon Mendoza Del Solar; Harriet Kemp; Lance M McCracken; Amanda C de C Williams; Andrew S C Rice Journal: Pain Date: 2020-05 Impact factor: 7.926
Authors: Charlotte C M van Laake-Geelen; Rob J E M Smeets; Marielle E J B Goossens; Jeanine A Verbunt Journal: J Rehabil Med Clin Commun Date: 2021-02-10
Authors: Charlotte C M Van Laake-Geelen; Rob J E M Smeets; Thijs Van Meulenbroek; Marlies Den Hollander; Marielle E J B Goossens; Jeanine A Verbunt Journal: J Rehabil Med Clin Commun Date: 2019-06-15
Authors: Mohammadreza Davoudi; Parnian Rezaei; Fereshteh Rajaeiramsheh; Seyed Majid Ahmadi; Amir Abbas Taheri Journal: Health Qual Life Outcomes Date: 2021-02-09 Impact factor: 3.186