Literature DB >> 28656377

Acute toxic leukoencephalopathy associated with a non-prescription weight loss supplement: a report of two cases.

Cesar E Escamilla-Ocañas1, Carlos R Cámara-Lemarroy1,2, Leonel Cantú-Martinez1, Héctor R Martínez3,4.   

Abstract

Weight loss dietary supplements are used with some frequency by an increasingly overweight population. Some products are not adequately regulated and may pose potential health risks. We report two new cases of acute toxic leukoencephalopathy (ATL) due to the use of a supplement marketed as a thermogenic weight loss aid. ATL is a heterogeneous clinic-radiological entity that has been associated with various compounds, such as chemotherapeutic drugs and immunomodulators. It is characterized by an often reversible periventricular and infratentorial demyelination. The commercialization of non-regulated weight loss products continues to be a health risk in our population.

Entities:  

Keywords:  Dietary supplements; Leukoencephalopathy; MRI; Toxic leukoencephalopathy; White matter

Mesh：

Substances：

Year:  2017        PMID： 28656377     DOI： 10.1007/s10072-017-3028-0

Source DB:  PubMed          Journal:  Neurol Sci        ISSN： 1590-1874            Impact factor:   3.307


  8 in total

Review 1.  Toxic leukoencephalopathy.

Authors:  C M Filley; B K Kleinschmidt-DeMasters
Journal:  N Engl J Med       Date:  2001-08-09       Impact factor: 91.245

2.  [Toxic demyelinating neuropathy and leukoencephalopathy in patients who take the slimming products Thermatrim ® and Pura Alegria ®].

Authors:  M Teresa Osuna; Luis Querol; Cristina I Olivas-Chacón; Saioa Lejarreta-Andrés; Jordi Robert; Nadim Ailouti-Caballero; Luis Ramos-Durán; Jordi Díaz-Manera; Robert Belvís
Journal:  Rev Neurol       Date:  2015-12-01       Impact factor: 0.870

3.  Leukoencephalopathic changes on magnetic resonance imaging associated with a thermogenic dietary supplement (Thermatrim).

Authors:  Cristina I Olivas-Chacon; Manuel Treviño-Garcia; John James Chua-Tuan; Jose M Rodriguez-Cordero; Alfonso H Gil-Valadez; Nassim Akle; Jesus E Calleros; Luis R Ramos-Duran
Journal:  Proc (Bayl Univ Med Cent)       Date:  2015-07

4.  Supplementation prevalence and adverse effects in physical exercise practitioners.

Authors:  Walkíria Valeriano da Silva; Maria Irene de Andrade Gomes Silva; Luciana Tavares Toscano; Klébya Hellen Dantas de Oliveira; Lavoisiana Mateus de Lacerda; Alexandre Sérgio Silva
Journal:  Nutr Hosp       Date:  2014-01-01       Impact factor: 1.057

5.  Dietary supplements in a national survey: Prevalence of use and reports of adverse events.

Authors:  Babgaleh B Timbo; Marianne P Ross; Patrick V McCarthy; Chung-Tung J Lin
Journal:  J Am Diet Assoc       Date:  2006-12

Review 6.  Toxic leukoencephalopathies, including drug, medication, environmental, and radiation-induced encephalopathic syndromes.

Authors:  Carolina de Medeiros Rimkus; Celi Santos Andrade; Claudia da Costa Leite; Alexander M McKinney; Leandro Tavares Lucato
Journal:  Semin Ultrasound CT MR       Date:  2014-04       Impact factor: 1.875

Review 7.  [A systematic review of the effectiveness of alternative weight-loss products' ingredients].

Authors:  Cynthia de Lira-García; María Souto-Gallardo; Monserrat Bacardí-Gascón; Arturo Jiménez-Cruz
Journal:  Rev Salud Publica (Bogota)       Date:  2008 Nov-Dec

8.  Acute toxic leukoencephalopathy: potential for reversibility clinically and on MRI with diffusion-weighted and FLAIR imaging.

Authors:  Alexander M McKinney; Stephen A Kieffer; Rogerich T Paylor; Karen S SantaCruz; Ayse Kendi; Leandro Lucato
Journal:  AJR Am J Roentgenol       Date:  2009-07       Impact factor: 3.959
  8 in total

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