Literature DB >> 28654827

Characterisation of the Medipix3 detector for 60 and 80keV electrons.

J A Mir1, R Clough1, R MacInnes2, C Gough2, R Plackett3, I Shipsey3, H Sawada4, I MacLaren2, R Ballabriga5, D Maneuski2, V O'Shea2, D McGrouther6, A I Kirkland7.   

Abstract

In this paper we report quantitative measurements of the imaging performance for the current generation of hybrid pixel detector, Medipix3, used as a direct electron detector. We have measured the modulation transfer function and detective quantum efficiency at beam energies of 60 and 80keV. In single pixel mode, energy threshold values can be chosen to maximize either the modulation transfer function or the detective quantum efficiency, obtaining values near to, or exceeding those for a theoretical detector with square pixels. The Medipix3 charge summing mode delivers simultaneous, high values of both modulation transfer function and detective quantum efficiency. We have also characterized the detector response to single electron events and describe an empirical model that predicts the detector modulation transfer function and detective quantum efficiency based on energy threshold. Exemplifying our findings we demonstrate the Medipix3 imaging performance recording a fully exposed electron diffraction pattern at 24-bit depth together with images in single pixel and charge summing modes. Our findings highlight that for transmission electron microscopy performed at low energies (energies <100keV) thick hybrid pixel detectors provide an advantageous architecture for direct electron imaging.
Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.

Keywords:  Charge summing mode; DQE; Medipix3; Nyquist frequency; Single pixel mode; TEM, MTF

Year:  2017        PMID: 28654827     DOI: 10.1016/j.ultramic.2017.06.010

Source DB:  PubMed          Journal:  Ultramicroscopy        ISSN: 0304-3991            Impact factor:   2.689


  11 in total

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2.  Automatic parameter selection for electron ptychography via Bayesian optimization.

Authors:  Michael C Cao; Zhen Chen; Yi Jiang; Yimo Han
Journal:  Sci Rep       Date:  2022-07-19       Impact factor: 4.996

3.  Synthesis and Properties of a Compositional Series of MIL-53(Al) Metal-Organic Framework Crystal-Glass Composites.

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4.  Atomic Resolution Defocused Electron Ptychography at Low Dose with a Fast, Direct Electron Detector.

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Journal:  Sci Rep       Date:  2019-03-08       Impact factor: 4.379

5.  Atomic electrostatic maps of 1D channels in 2D semiconductors using 4D scanning transmission electron microscopy.

Authors:  Shiang Fang; Yi Wen; Christopher S Allen; Colin Ophus; Grace G D Han; Angus I Kirkland; Efthimios Kaxiras; Jamie H Warner
Journal:  Nat Commun       Date:  2019-03-08       Impact factor: 14.919

6.  CryoEM at 100 keV: a demonstration and prospects.

Authors:  K Naydenova; G McMullan; M J Peet; Y Lee; P C Edwards; S Chen; E Leahy; S Scotcher; R Henderson; C J Russo
Journal:  IUCrJ       Date:  2019-10-11       Impact factor: 4.769

7.  An electron counting algorithm improves imaging of proteins with low-acceleration-voltage cryo-electron microscope.

Authors:  Dongjie Zhu; Huigang Shi; Chunling Wu; Xinzheng Zhang
Journal:  Commun Biol       Date:  2022-04-06

8.  Electron crystallography with the EIGER detector.

Authors:  Gemma Tinti; Erik Fröjdh; Eric van Genderen; Tim Gruene; Bernd Schmitt; D A Matthijs de Winter; Bert M Weckhuysen; Jan Pieter Abrahams
Journal:  IUCrJ       Date:  2018-02-14       Impact factor: 4.769

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Authors:  Zhen Chen; Michal Odstrcil; Yi Jiang; Yimo Han; Ming-Hui Chiu; Lain-Jong Li; David A Muller
Journal:  Nat Commun       Date:  2020-06-12       Impact factor: 14.919

10.  Low-dose phase retrieval of biological specimens using cryo-electron ptychography.

Authors:  Liqi Zhou; Jingdong Song; Judy S Kim; Xudong Pei; Chen Huang; Mark Boyce; Luiza Mendonça; Daniel Clare; Alistair Siebert; Christopher S Allen; Emanuela Liberti; David Stuart; Xiaoqing Pan; Peter D Nellist; Peijun Zhang; Angus I Kirkland; Peng Wang
Journal:  Nat Commun       Date:  2020-06-02       Impact factor: 17.694

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