Literature DB >> 28654410

Audiologic Assessment in Adults With Down Syndrome.

Pasqualina M Picciotti1, Angelo Carfì1, Roberta Anzivino1, Gaetano Paludetti1, Guido Conti1, Vincenzo Brandi1, Roberto Bernabei1, Graziano Onder1.   

Abstract

Increased life expectancy in persons with Down syndrome (DS) is associated with premature age-related changes. The aim of this study was to assess auditory function in adults with DS and to evaluate the prevalence of hearing loss in this population. Audiometric tests were performed in 72 adults with DS (mean age 37.3±10.1 years, 51.4% females). Air conduction pure tone average (PTA) thresholds at frequencies 0.5-1-2-4 kHz were calculated to assess hearing function. Hearing loss was present if the PTA threshold was > 20 dB hearing level. Higher frequencies of 4 and 8 kHz were also assessed. Hearing loss was shown in 47 (65.3%) participants. The prevalence of hearing loss increased with age, ranging from 42.86% in the 20-29 years group to 90.91% in the 50-59 years group. High frequencies (4 and 8 kHz) were more often impaired than other frequencies used to measure PTA. Thus, the study concluded hearing loss is common in adults with DS and shows a pattern compatible with precocious aging of the hearing system. Auditory evaluation is strongly recommended in adults with DS.

Entities:  

Keywords:  Down syndrome; aging; hearing; presbycusis

Mesh:

Year:  2017        PMID: 28654410     DOI: 10.1352/1944-7558-122.4.333

Source DB:  PubMed          Journal:  Am J Intellect Dev Disabil        ISSN: 1944-7558


  5 in total

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Journal:  Metab Brain Dis       Date:  2017-09-30       Impact factor: 3.584

Review 2.  Neurologic complications of Down syndrome: a systematic review.

Authors:  Jonathan D Santoro; Dania Pagarkar; Duong T Chu; Mattia Rosso; Kelli C Paulsen; Pat Levitt; Michael S Rafii
Journal:  J Neurol       Date:  2020-09-12       Impact factor: 6.682

3.  Health comorbidities and cognitive abilities across the lifespan in Down syndrome.

Authors:  Carla M Startin; Hana D'Souza; George Ball; Sarah Hamburg; Rosalyn Hithersay; Kate M O Hughes; Esha Massand; Annette Karmiloff-Smith; Michael S C Thomas; Andre Strydom
Journal:  J Neurodev Disord       Date:  2020-01-23       Impact factor: 4.025

4.  Opportunities, barriers, and recommendations in down syndrome research.

Authors:  James A Hendrix; Angelika Amon; Leonard Abbeduto; Stamatis Agiovlasitis; Tarek Alsaied; Heather A Anderson; Lisa J Bain; Nicole Baumer; Anita Bhattacharyya; Dusan Bogunovic; Kelly N Botteron; George Capone; Priya Chandan; Isabelle Chase; Brian Chicoine; Cécile Cieuta-Walti; Lara R DeRuisseau; Sophie Durand; Anna Esbensen; Juan Fortea; Sandra Giménez; Ann-Charlotte Granholm; Laura J Hahn; Elizabeth Head; Hampus Hillerstrom; Lisa M Jacola; Matthew P Janicki; Joan M Jasien; Angela R Kamer; Raymond D Kent; Bernard Khor; Jeanne B Lawrence; Catherine Lemonnier; Amy Feldman Lewanda; William Mobley; Paul E Moore; Linda Pollak Nelson; Nicolas M Oreskovic; Ricardo S Osorio; David Patterson; Sonja A Rasmussen; Roger H Reeves; Nancy Roizen; Stephanie Santoro; Stephanie L Sherman; Nasreen Talib; Ignacio E Tapia; Kyle M Walsh; Steven F Warren; A Nicole White; Guang William Wong; John S Yi
Journal:  Transl Sci Rare Dis       Date:  2021-04-15

5.  Mechanistic Analysis of Age-Related Clinical Manifestations in Down Syndrome.

Authors:  Xu-Qiao Chen; Zhuo Xing; Quang-Di Chen; Richard J Salvi; Xuming Zhang; Benjamin Tycko; William C Mobley; Y Eugene Yu
Journal:  Front Aging Neurosci       Date:  2021-07-01       Impact factor: 5.750

  5 in total

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