Literature DB >> 28654326

The Ubiquitin System, Autophagy, and Regulated Protein Degradation.

Alexander Varshavsky1.   

Abstract

This brief disquisition about the early history of studies on regulated protein degradation introduces several detailed reviews about the ubiquitin system and autophagy.

Keywords:  N-end rule; autophagy; polyubiquitin; proteasome; protein degradation; ubiquitin; ubiquitin-like

Mesh：

Substances：

Year:  2017        PMID： 28654326     DOI： 10.1146/annurev-biochem-061516-044859

Source DB:  PubMed          Journal:  Annu Rev Biochem        ISSN： 0066-4154            Impact factor:   23.643


  99 in total

Review 1.  Biochemistry and Molecular Biology of Flaviviruses.

Authors:  Nicholas J Barrows; Rafael K Campos; Kuo-Chieh Liao; K Reddisiva Prasanth; Ruben Soto-Acosta; Shih-Chia Yeh; Geraldine Schott-Lerner; Julien Pompon; October M Sessions; Shelton S Bradrick; Mariano A Garcia-Blanco
Journal:  Chem Rev       Date:  2018-04-13       Impact factor: 60.622

2.  Kelch-like protein 42 is a profibrotic ubiquitin E3 ligase involved in systemic sclerosis.

Authors:  Travis B Lear; Karina C Lockwood; Mads Larsen; Ferhan Tuncer; Jason R Kennerdell; Christina Morse; Eleanor Valenzi; Tracy Tabib; Michael J Jurczak; Daniel J Kass; John W Evankovich; Toren Finkel; Robert Lafyatis; Yuan Liu; Bill B Chen
Journal:  J Biol Chem       Date:  2020-02-17       Impact factor: 5.157

Review 3.  Protein-protein interaction modulators: advances, successes and remaining challenges.

Authors:  Lloyd Mabonga; Abidemi Paul Kappo
Journal:  Biophys Rev       Date:  2019-07-12

4.  Downregulation of autophagy by Met30-mediated Atg9 ubiquitination.

Authors:  Yuchen Feng; Aileen R Ariosa; Ying Yang; Zehan Hu; Jörn Dengjel; Daniel J Klionsky
Journal:  Proc Natl Acad Sci U S A       Date:  2021-01-05       Impact factor: 11.205

5.  Mutations in ADNP affect expression and subcellular localization of the protein.

Authors:  Elisa Cappuyns; Jolien Huyghebaert; Geert Vandeweyer; R Frank Kooy
Journal:  Cell Cycle       Date:  2018-07-17       Impact factor: 4.534

6.  Everolimus induces G1 cell cycle arrest through autophagy-mediated protein degradation of cyclin D1 in breast cancer cells.

Authors:  Guang Chen; Xiao-Fei Ding; Hakim Bouamar; Kyle Pressley; Lu-Zhe Sun
Journal:  Am J Physiol Cell Physiol       Date:  2019-05-22       Impact factor: 4.249

Review 7.  The structure and regulation of the E3 ubiquitin ligase HUWE1 and its biological functions in cancer.

Authors:  Xiaofeng Gong; Danyu Du; Yanran Deng; Yuqi Zhou; Li Sun; Shengtao Yuan
Journal:  Invest New Drugs       Date:  2020-02-01       Impact factor: 3.850

8.  Therapeutic targeting of HER2-CB2R heteromers in HER2-positive breast cancer.

Authors:  Sandra Blasco-Benito; Estefanía Moreno; Marta Seijo-Vila; Isabel Tundidor; Clara Andradas; María M Caffarel; Miriam Caro-Villalobos; Leyre Urigüen; Rebeca Diez-Alarcia; Gema Moreno-Bueno; Lucía Hernández; Luis Manso; Patricia Homar-Ruano; Peter J McCormick; Lucka Bibic; Cristina Bernadó-Morales; Joaquín Arribas; Meritxell Canals; Vicent Casadó; Enric I Canela; Manuel Guzmán; Eduardo Pérez-Gómez; Cristina Sánchez
Journal:  Proc Natl Acad Sci U S A       Date:  2019-02-07       Impact factor: 11.205

9.  A cell-based high-throughput screening method based on a ubiquitin-reference technique for identifying modulators of E3 ligases.

Authors:  Maoyuan Tian; Taoling Zeng; Mingdong Liu; Shang Han; Huayue Lin; Qi Lin; Li Li; Tingting Jiang; Gao Li; Hong Lin; Ting Zhang; Qiaofeng Kang; Xianming Deng; Hong-Rui Wang
Journal:  J Biol Chem       Date:  2018-12-26       Impact factor: 5.157

Review 10.  Functional analysis of Cullin 3 E3 ligases in tumorigenesis.

Authors:  Ji Cheng; Jianping Guo; Zhiwei Wang; Brian J North; Kaixiong Tao; Xiangpeng Dai; Wenyi Wei
Journal:  Biochim Biophys Acta Rev Cancer       Date:  2017-11-08       Impact factor: 10.680
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