Brian Pietrosimone1,2, Brittney A Luc1,2, Austin Duncan1, Susan A Saliba3, Joseph M Hart3, Christopher D Ingersoll4. 1. Exercise and Sport Science and. 2. Human Movement Science Curriculum, University of North Carolina at Chapel Hill. 3. Department of Kinesiology, University of Virginia, Charlottesville. 4. School of Exercise and Rehabilitation Sciences, University of Toledo, OH.
Abstract
CONTEXT: Patient-reported outcomes (PROs) evaluate how patients describe symptoms as well as level of physical function or quality of life. The Western Ontario and McMaster Universities Osteoarthritis (WOMAC) Index is one of the most common PROs used to assess disability in patients with knee osteoarthritis (OA), yet the Single Assessment Numeric Evaluation (SANE) is a single-question instrument that may improve the efficiency associated with the measurement of patient function. OBJECTIVE: To determine the associations between (1) SANEFunction and the physical dysfunction subsection of the WOMAC index (WOMACDysfunction) before rehabilitation and after a 4-week therapeutic exercise intervention as well as (2) the percentage change in SANEFunction and WOMACDysfunction in people with knee OA after 4 weeks of therapeutic exercise. DESIGN: Cross-sectional study. SETTING: Research laboratory. PATIENTS OR OTHER PARTICIPANTS: Thirty-six participants (15 men, 21 women) with radiographic knee OA. INTERVENTION(S): Participants completed 12 sessions (over a 4-week period) of therapeutic exercise to strengthen the lower extremity. MAIN OUTCOME MEASURE(S): The SANEFunction and WOMACDysfunction (WOMACDysfunction normalized to 100%) scores were collected before and after the 4-week intervention. Percentage change scores over the 4-week intervention were calculated for both measures. RESULTS: Participants with a higher SANEFunction score demonstrated a lower WOMACDysfunction score at baseline (rs = -0.44, P = .007) and at the 4-week time point (rs = -0.69, P < .001). There was a nonsignificant and weak association between the changes in the SANEFunction and WOMACDysfunction scores over the 4 weeks of therapeutic exercise (rs = -0.17, P < .43). CONCLUSIONS: The SANEFunction and WOMACDysfunction scores demonstrated moderate to weak associations before and after a 4-week exercise program, respectively, whereas the changes in SANEFunction and WOMACDysfunction scores were not associated. These PROs may be measuring different aspects of self-reported function and therefore should not be used interchangeably to determine a therapeutic response.
CONTEXT: Patient-reported outcomes (PROs) evaluate how patients describe symptoms as well as level of physical function or quality of life. The Western Ontario and McMaster Universities Osteoarthritis (WOMAC) Index is one of the most common PROs used to assess disability in patients with knee osteoarthritis (OA), yet the Single Assessment Numeric Evaluation (SANE) is a single-question instrument that may improve the efficiency associated with the measurement of patient function. OBJECTIVE: To determine the associations between (1) SANEFunction and the physical dysfunction subsection of the WOMAC index (WOMACDysfunction) before rehabilitation and after a 4-week therapeutic exercise intervention as well as (2) the percentage change in SANEFunction and WOMACDysfunction in people with knee OA after 4 weeks of therapeutic exercise. DESIGN: Cross-sectional study. SETTING: Research laboratory. PATIENTS OR OTHER PARTICIPANTS: Thirty-six participants (15 men, 21 women) with radiographic knee OA. INTERVENTION(S): Participants completed 12 sessions (over a 4-week period) of therapeutic exercise to strengthen the lower extremity. MAIN OUTCOME MEASURE(S): The SANEFunction and WOMACDysfunction (WOMACDysfunction normalized to 100%) scores were collected before and after the 4-week intervention. Percentage change scores over the 4-week intervention were calculated for both measures. RESULTS:Participants with a higher SANEFunction score demonstrated a lower WOMACDysfunction score at baseline (rs = -0.44, P = .007) and at the 4-week time point (rs = -0.69, P < .001). There was a nonsignificant and weak association between the changes in the SANEFunction and WOMACDysfunction scores over the 4 weeks of therapeutic exercise (rs = -0.17, P < .43). CONCLUSIONS: The SANEFunction and WOMACDysfunction scores demonstrated moderate to weak associations before and after a 4-week exercise program, respectively, whereas the changes in SANEFunction and WOMACDysfunction scores were not associated. These PROs may be measuring different aspects of self-reported function and therefore should not be used interchangeably to determine a therapeutic response.
Entities:
Keywords:
disability; patient-reported outcomes; physical function; quality of life
Authors: Marita Cross; Emma Smith; Damian Hoy; Sandra Nolte; Ilana Ackerman; Marlene Fransen; Lisa Bridgett; Sean Williams; Francis Guillemin; Catherine L Hill; Laura L Laslett; Graeme Jones; Flavia Cicuttini; Richard Osborne; Theo Vos; Rachelle Buchbinder; Anthony Woolf; Lyn March Journal: Ann Rheum Dis Date: 2014-02-19 Impact factor: 19.103