Literature DB >> 28653761

A prospective clinical study of regenerative endodontic treatment of traumatized immature teeth with necrotic pulps using bi-antibiotic paste.

H Nazzal1, K Kenny1, A Altimimi1, J Kang2, M S Duggal1.   

Abstract

AIM: To evaluate the treatment outcomes of a revitalization endodontic technique (RET) for the management of traumatized immature teeth with necrotic pulps in children.
METHODOLOGY: Fifteen healthy children (age range = 7-10 years) with traumatized immature maxillary incisors with necrotic pulps treated with bi-antibiotic revitalization endodontic technique were prospectively assessed over approximately two years (mean = 22 months). One operator undertook all treatments, clinical reviews and standardized radiographic exposures with radiographic analysis being carried out by two calibrated experienced clinicians. Crown colour change was assessed using an objective published methodology. Wilcoxon signed-rank test was used to compare root lengths, root dentinal widths and apical foramen widths over time.
RESULTS: Interoperator measurement reliability was consistently strong for all measurements. There was no significant difference in root lengths or root dentinal wall widths following RET. A significant difference in apical foramen widths was observed after 2 years (P = 0.013) with resolution of clinical signs of infection in all cases. Despite omitting minocycline and using Portland cement (nonbismuth containing cement), a noticeable crown colour change (yellower, redder and lighter), as measured by an objective colour measurement system with ΔE = 7.39, was recorded. Most patients, however, were satisfied with the aesthetic outcome.
CONCLUSION: Traumatized immature teeth with necrotic pulps treated with revitalization endodontic technique did not demonstrate continuation of root development or dentine formation when assessed by periapical radiographs. However, apical closure and periodontal healing were observed. A measurable change in crown colour (yellower, redder and lighter), with mostly no aesthetic concern to the patients/parents, was also observed.
© 2017 International Endodontic Journal. Published by John Wiley & Sons Ltd.

Entities:  

Keywords:  dental trauma; immature teeth; nonvital teeth; revitalisation endodontic treatment

Mesh:

Substances:

Year:  2017        PMID: 28653761     DOI: 10.1111/iej.12808

Source DB:  PubMed          Journal:  Int Endod J        ISSN: 0143-2885            Impact factor:   5.264


  8 in total

1.  Regenerative endodontic therapy for managing immature non-vital teeth: a national survey of UK paediatric dental specialists and trainees.

Authors:  H Nazzal; H Tong; P Nixon; M Duggal
Journal:  Br Dent J       Date:  2018-02-23       Impact factor: 1.626

2.  "Meta-analysis of regenerative endodontics outcomes with antibiotics pastes and calcium hydroxide. The apex of the iceberg".

Authors:  Viviana Báez; Lorena Corcos; Florencia Morgillo; Lorena Imperatrice; Ariel Félix Gualtieri
Journal:  J Oral Biol Craniofac Res       Date:  2021-11-10

3.  Regenerative Endodontic Procedure in an Immature Permanent Incisor with Internal Root Resorption: a Case Report.

Authors:  Gaizka Loroño; Antonio Jesús Conde; Roberto Estévez; Claudia Brizuela; Rafael Cisneros; Ruth Pérez Alfayate
Journal:  J Dent (Shiraz)       Date:  2022-06

4.  Platelet-rich fibrin and collagen matrix for the regeneration of infected necrotic immature teeth.

Authors:  S Sakthivel; V Gayathri; Subha Anirudhan; R Jaya Shree Roja
Journal:  J Clin Transl Res       Date:  2020-07-08

5.  A comparative evaluation of Advanced Platelet-Rich Fibrin (A-PRF) and Platelet-Rich Fibrin (PRF) as a Scaffold in Regenerative Endodontic Treatment of Traumatized Immature Non-vital permanent anterior teeth: A Prospective clinical study.

Authors:  Veena Jayadevan; Paras-Mull Gehlot; Vinutha Manjunath; Subbarao V Madhunapantula; Jyothi-Swandenahalli Lakshmikanth
Journal:  J Clin Exp Dent       Date:  2021-05-01

6.  Ex-vivo recellularisation and stem cell differentiation of a decellularised rat dental pulp matrix.

Authors:  Manal Matoug-Elwerfelli; Hani Nazzal; El Mostafa Raif; Stacy-Paul Wilshaw; Filomena Esteves; Monty Duggal
Journal:  Sci Rep       Date:  2020-12-09       Impact factor: 4.379

7.  Human Amnion Epithelial Cells: A Potential Cell Source for Pulp Regeneration?

Authors:  Cristina Bucchi; Ella Ohlsson; Josep Maria de Anta; Melanie Woelflick; Kerstin Galler; María Cristina Manzanares-Cespedes; Matthias Widbiller
Journal:  Int J Mol Sci       Date:  2022-03-04       Impact factor: 5.923

8.  What is the best long-term treatment modality for immature permanent teeth with pulp necrosis and apical periodontitis?

Authors:  A Wikström; M Brundin; M F Lopes; M El Sayed; G Tsilingaridis
Journal:  Eur Arch Paediatr Dent       Date:  2021-01-08
  8 in total

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