| Literature DB >> 28653739 |
L Yang1, Y Teng2, T-P Han1, F-G Li1, W-T Yue2, Z-T Wang3.
Abstract
Lung cancer is the leading cause of cancer death in men and the second leading cause of cancer death in women worldwide. Fascin-1 and laminin-5 were associated with the invasiveness and prognoses of several cancers. The expression and the serum levels of fascin-1 and laminin-5 in patients with non-small cell lung cancer (NSCLC) were analyzed in this study. The expression of fascin-1 and laminin-5 were examined in 378 patients and their serum level was measured in 154 patients. The health of all patients was followed post-surgery. The expression of fascin-1 (P = 0.000) and lanminin-5 (P = 0.001) and the serum levels of fascin-1 (P = 0.015) and laminin-5 (P = 0.046) were related to the relapse of patients with NSCLC. Both serum levels and expression of fascin-1 and laminin-5 can be used to effectively evaluate the prognoses of patients with NSCLC.Entities:
Mesh：
Substances：
Year: 2017 PMID： 28653739 DOI： 10.4238/gmr16029617
Source DB: PubMed Journal: Genet Mol Res ISSN： 1676-5680