Hashem Sharghi1, Saeideh Sepehri2, Mahdi Aberi2. 1. Department of Chemistry, Shiraz University, Shiraz, 71454, Islamic Republic of Iran. shashem@susc.ac.ir. 2. Department of Chemistry, Shiraz University, Shiraz, 71454, Islamic Republic of Iran.
Abstract
In this paper, a highly reusable copper(II) complex of pyridine-based polydentate is able to efficiently catalyze a C-N bond-forming reaction under mild conditions. A variety of N-heterocyclic and amine compounds arylated with different aryl iodides, bromides, and chlorides produced N-substituted compounds in good to excellent yields. This methodology can be also used for the arylation of N-unsubstituted compounds using arylboronic acids under solvent-free conditions. All reactions are performed in short times under air, and the catalyst can be reused up to seven times.
In this paper, a highly reusable copper(II) complex of n class="Chemical">pyridine-based polydentate is able to efficiently catalyze a C-N bond-forming reaction under mild conditions. A variety of N-heterocyclic and amine compounds arylated with different aryl iodides, bromides, and chlorides produced N-substituted compounds in good to excellent yields. This methodology can be also used for the arylation of N-unsubstituted compounds using arylboronic acids under solvent-free conditions. All reactions are performed in short times under air, and the catalyst can be reused up to seven times.