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Literature DB >> 2865021

Somatostatin and water excretion in man: an intrarenal action.

B J Walker, P A Evans, M L Forsling, G A Nelstrop.

Abstract

Intravenous infusion of somatostatin in six water loaded normal human subjects produced a prompt reduction in urine flow accompanied by a rise in urine osmolality and a decrease in free water clearance. Plasma AVP levels did not change. Somatostatin would seem to exert an antidiuretic effect directly on the kidney.

Entities: Chemical Gene Species

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Year: 1985 PMID： 2865021 DOI： 10.1111/j.1365-2265.1985.tb00212.x

Source DB: PubMed Journal: Clin Endocrinol (Oxf) ISSN： 0300-0664 Impact factor: 3.478

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Cited

6 in total

1. Association of plasma somatostatin with disease severity and progression in patients with autosomal dominant polycystic kidney disease.

Authors: A Lianne Messchendorp; Edwin M Spithoven; Niek F Casteleijn; Wendy A Dam; Jacob van den Born; Wouter F Tonnis; Carlo A J M Gaillard; Esther Meijer
Journal: BMC Nephrol Date: 2018-12-19 Impact factor: 2.388

Somatostatin and water excretion in man: an intrarenal action.

1. Association of plasma somatostatin with disease severity and progression in patients with autosomal dominant polycystic kidney disease.

2. Effect of somatostatin on kidney function and vasoactive hormone systems in health subjects.

Review 3. Drug-induced syndrome of inappropriate antidiuretic hormone secretion. Causes, diagnosis and management.

4. Tolvaptan plus pasireotide shows enhanced efficacy in a PKD1 model.

5. Effect of somatostatin on renal function.

6. Effect of a Somatostatin Analogue on the Vasopressin Pathway in Patients With ADPKD.