Literature DB >> 28649858

Two new protostane-type triterpenoids from Alisma orientalis.

Xiu-Lan Xin1,2, Xin-Yu Zhao2,3, Xiao-Kui Huo2, Xiang-Ge Tian4, Cheng-Peng Sun2, Hou-Li Zhang2, Yan Tian2, Yong Liu3, Xun Wang5.   

Abstract

Two new protostane-type triterpenoids, 17-epi alisolide (1) and 24-epi alismanol D (2), were isolated from Alisma orientalis together with one known compound. Their structural elucidations were conducted by NMR, UV and HRESIMS spectroscopic analyses, and comparison with the literature data. All the isolated compounds were evaluated for inhibitory effects on HCE-2. Compound 2 displayed moderate inhibitory activity against HCE-2 with IC50 value of 23.1 μM.

Entities:  

Keywords:  Alisma orientalis; HCE-2; protostane-type triterpenoid

Mesh:

Substances:

Year:  2017        PMID: 28649858     DOI: 10.1080/14786419.2017.1344660

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN: 1478-6419            Impact factor:   2.861


  3 in total

Review 1.  Triterpenoids From Alisma Species: Phytochemistry, Structure Modification, and Bioactivities.

Authors:  Pengli Wang; Tongxin Song; Rui Shi; Mingshuai He; Rongrong Wang; Jialin Lv; Miaomiao Jiang
Journal:  Front Chem       Date:  2020-04-30       Impact factor: 5.221

2.  Simultaneous Determination of the Five Constituents in Maiwei Dihuang Pills by the HPLC-DAD Method.

Authors:  Danchun Jia; Hong Cai; Yuan Ke
Journal:  Evid Based Complement Alternat Med       Date:  2021-09-02       Impact factor: 2.629

3.  Methyl jasmonate promote protostane triterpenes accumulation by up-regulating the expression of squalene epoxidases in Alisma orientale.

Authors:  Rong Tian; Wei Gu; Yuchen Gu; Chao Geng; Fei Xu; Qinan Wu; Jianguo Chao; Wenda Xue; Chen Zhou; Fan Wang
Journal:  Sci Rep       Date:  2019-12-02       Impact factor: 4.379

  3 in total

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