| Literature DB >> 28649730 |
Misun Hwang1, Robert M De Jong1, Stephan Herman1, Renee Boss2, Becky Riggs3, Aylin Tekes-Brady1, Melissa Spevak1, Andrea Poretti1, Bruno P Soares1, Christopher R Bailey1, Emily Dunn1, Samuel S Shin4, Shai Shrot1, Thierry A G M Huisman1.
Abstract
Sensitive, specific, and safe bedside evaluation of brain perfusion is key to the early diagnosis, treatment, and improved survival of neonates with hypoxic ischemic injury. Contrast-enhanced ultrasound (US) imaging is a novel imaging technique in which intravenously injected gas-filled microbubbles generate enhanced US echoes from an acoustic impedance mismatch. This article describes contrast-enhanced US imaging in 2 neonates with hypoxic ischemic injury and future directions on developing quantitative contrast-enhanced US techniques for improved characterization of perfusion abnormalities. The importance of studying the temporal evolution of brain perfusion in neonatal hypoxic ischemic injury is also highlighted.Entities:
Keywords: contrast-enhanced ultrasound; hypoxic ischemic injury; microbubbles; neonates; neuroimaging; pediatric ultrasound
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Year: 2017 PMID： 28649730 DOI： 10.1002/jum.14289
Source DB: PubMed Journal: J Ultrasound Med ISSN： 0278-4297 Impact factor: 2.153