Literature DB >> 28646957

Whither vaccines?

Charlene M C Rodrigues1, Marta V Pinto2, Manish Sadarangani3, Stanley A Plotkin4.   

Abstract

Currently used vaccines have had major effects on eliminating common infections, largely by duplicating the immune responses induced by natural infections. Now vaccinology faces more complex problems, such as waning antibody, immunosenescence, evasion of immunity by the pathogen, deviation of immunity by the microbiome, induction of inhibitory responses, and complexity of the antigens required for protection. Fortunately, vaccine development is now incorporating knowledge from immunology, structural biology, systems biology and synthetic chemistry to meet these challenges. In addition, international organisations are developing new funding and licensing pathways for vaccines aimed at pathogens with epidemic potential that emerge from tropical areas.
© 2017 The British Infection Association. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  CMV; Dengue; HIV; Host immunity; Influenza; Pertussis; RSV; Rotavirus; Structural biology; Vaccinology

Mesh：

Substances：

Year:  2017        PMID： 28646957      PMCID： PMC7172359          DOI： 10.1016/S0163-4453(17)30184-6

Source DB:  PubMed          Journal:  J Infect        ISSN： 0163-4453            Impact factor:   6.072


  81 in total

Review 1.  Recent advances in the molecular design of synthetic vaccines.

Authors:  Lyn H Jones
Journal:  Nat Chem       Date:  2015-12       Impact factor: 24.427

Review 2.  Summary of effectiveness and impact of rotavirus vaccination with the oral pentavalent rotavirus vaccine: a systematic review of the experience in industrialized countries.

Authors:  Carlo Giaquinto; Geraldine Dominiak-Felden; Pierre Van Damme; Tin Tin Htar Myint; Yvonne A Maldonado; Vana Spoulou; T Christopher Mast; Mary Allen Staat
Journal:  Hum Vaccin       Date:  2011-07-01

3.  Enveloped virus-like particle expression of human cytomegalovirus glycoprotein B antigen induces antibodies with potent and broad neutralizing activity.

Authors:  Marc Kirchmeier; Anne-Catherine Fluckiger; Catalina Soare; Jasminka Bozic; Barthelemy Ontsouka; Tanvir Ahmed; Abebaw Diress; Lenore Pereira; Florian Schödel; Stanley Plotkin; Charlotte Dalba; David Klatzmann; David E Anderson
Journal:  Clin Vaccine Immunol       Date:  2013-12-11

4.  Multicenter trial of Towne strain attenuated virus vaccine in seronegative renal transplant recipients.

Authors:  S A Plotkin; R Higgins; J B Kurtz; P J Morris; D A Campbell; T C Shope; S A Spector; W M Dankner
Journal:  Transplantation       Date:  1994-12-15       Impact factor: 4.939

Review 5.  The history of vaccination against cytomegalovirus.

Authors:  Stanley Plotkin
Journal:  Med Microbiol Immunol       Date:  2015-03-20       Impact factor: 3.402

6.  Antibiotic treatment suppresses rotavirus infection and enhances specific humoral immunity.

Authors:  Robin Uchiyama; Benoit Chassaing; Benyue Zhang; Andrew T Gewirtz
Journal:  J Infect Dis       Date:  2014-01-16       Impact factor: 5.226

7.  Acellular pertussis vaccines protect against disease but fail to prevent infection and transmission in a nonhuman primate model.

Authors:  Jason M Warfel; Lindsey I Zimmerman; Tod J Merkel
Journal:  Proc Natl Acad Sci U S A       Date:  2013-11-25       Impact factor: 11.205

8.  Intestinal microbiota promote enteric virus replication and systemic pathogenesis.

Authors:  Sharon K Kuss; Gavin T Best; Chris A Etheredge; Andrea J Pruijssers; Johnna M Frierson; Lora V Hooper; Terence S Dermody; Julie K Pfeiffer
Journal:  Science       Date:  2011-10-14       Impact factor: 47.728

Review 9.  Desirability and feasibility of a vaccine against cytomegalovirus.

Authors:  Paul Griffiths; Stanley Plotkin; Edward Mocarski; Robert Pass; Mark Schleiss; Philip Krause; Stephanie Bialek
Journal:  Vaccine       Date:  2013-04-18       Impact factor: 3.641

Review 10.  Influenza vaccines: a moving interdisciplinary field.

Authors:  Michael Schotsaert; Adolfo García-Sastre
Journal:  Viruses       Date:  2014-10-09       Impact factor: 5.048
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  11 in total

Review 1.  Subdominance in Antibody Responses: Implications for Vaccine Development.

Authors:  Gunnar Lindahl
Journal:  Microbiol Mol Biol Rev       Date:  2020-11-25       Impact factor: 11.056

Review 2.  mRNA vaccines - a new era in vaccinology.

Authors:  Norbert Pardi; Michael J Hogan; Frederick W Porter; Drew Weissman
Journal:  Nat Rev Drug Discov       Date:  2018-01-12       Impact factor: 84.694

3.  Targeted Amino Acid Substitution Overcomes Scale-Up Challenges with the Human C5a-Derived Decapeptide Immunostimulant EP67.

Authors:  Abdulraman M Alshammari; D David Smith; Jake Parriott; Jason P Stewart; Stephen M Curran; Russell J McCulloh; Peter A Barry; Smita S Iyer; Nicholas Palermo; Joy A Phillips; Yuxiang Dong; Donald R Ronning; Jonathan L Vennerstrom; Sam D Sanderson; Joseph A Vetro
Journal:  ACS Infect Dis       Date:  2020-04-13       Impact factor: 5.084

4.  Conformational Occlusion of Blockade Antibody Epitopes, a Novel Mechanism of GII.4 Human Norovirus Immune Evasion.

Authors:  Lisa C Lindesmith; Michael L Mallory; Kari Debbink; Eric F Donaldson; Paul D Brewer-Jensen; Excel W Swann; Timothy P Sheahan; Rachel L Graham; Martina Beltramello; Davide Corti; Antonio Lanzavecchia; Ralph S Baric
Journal:  mSphere       Date:  2018-02-07       Impact factor: 4.389

Review 5.  The establishment of surrogates and correlates of protection: Useful tools for the licensure of effective influenza vaccines?

Authors:  Brian J Ward; Stephane Pillet; Nathalie Charland; Sonia Trepanier; Julie Couillard; Nathalie Landry
Journal:  Hum Vaccin Immunother       Date:  2018-01-16       Impact factor: 3.452

6.  Skeletal Muscle Is an Antigen Reservoir in Integrase-Defective Lentiviral Vector-Induced Long-Term Immunity.

Authors:  Yi-Yu Lin; Ian Belle; Maria Blasi; Min-Nung Huang; Anne F Buckley; Wes Rountree; Mary E Klotman; Andrea Cara; Donatella Negri
Journal:  Mol Ther Methods Clin Dev       Date:  2020-03-13       Impact factor: 6.698

Review 7.  mRNA vaccine: a potential therapeutic strategy.

Authors:  Yang Wang; Ziqi Zhang; Jingwen Luo; Xuejiao Han; Yuquan Wei; Xiawei Wei
Journal:  Mol Cancer       Date:  2021-02-16       Impact factor: 27.401

Review 8.  An Overview on the Development of mRNA-Based Vaccines and Their Formulation Strategies for Improved Antigen Expression In Vivo.

Authors:  Md Motiar Rahman; Nan Zhou; Jiandong Huang
Journal:  Vaccines (Basel)       Date:  2021-03-11

Review 9.  Overview of SARS-CoV-2 infection in adults living with HIV.

Authors:  Juan Ambrosioni; José Luis Blanco; Juliana M Reyes-Urueña; Mary-Ann Davies; Omar Sued; Maria Angeles Marcos; Esteban Martínez; Silvia Bertagnolio; Jose Alcamí; Jose M Miro
Journal:  Lancet HIV       Date:  2021-05       Impact factor: 12.767

Review 10.  Influenza Viruses: Innate Immunity and mRNA Vaccines.

Authors:  SangJoon Lee; Jin-Hyeob Ryu
Journal:  Front Immunol       Date:  2021-08-31       Impact factor: 7.561
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