Literature DB >> 28645897

Versatility of presenilin 1.

Georgia R Frost1,2, Eitan Wong1, Yue-Ming Li3,2,4.   

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Year:  2017        PMID： 28645897      PMCID： PMC5502655          DOI： 10.1073/pnas.1707809114

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


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  30 in total

1.  Identification of new Presenilin-1 phosphosites: implication for γ-secretase activity and Aβ production.

Authors:  Alexandre Matz; Blanka Halamoda-Kenzaoui; Romain Hamelin; Sebastien Mosser; Jean-René Alattia; Mitko Dimitrov; Marc Moniatte; Patrick C Fraering
Journal:  J Neurochem       Date:  2015-02-24       Impact factor: 5.372

2.  Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1.

Authors:  K Duff; C Eckman; C Zehr; X Yu; C M Prada; J Perez-tur; M Hutton; L Buee; Y Harigaya; D Yager; D Morgan; M N Gordon; L Holcomb; L Refolo; B Zenk; J Hardy; S Younkin
Journal:  Nature       Date:  1996-10-24       Impact factor: 49.962

3.  Bidirectional regulation of Aβ levels by Presenilin 1.

Authors:  Victor Bustos; Maria V Pulina; Yildiz Kelahmetoglu; Subhash C Sinha; Fred S Gorelick; Marc Flajolet; Paul Greengard
Journal:  Proc Natl Acad Sci U S A       Date:  2017-05-22       Impact factor: 11.205

4.  Phosphorylated Presenilin 1 decreases β-amyloid by facilitating autophagosome-lysosome fusion.

Authors:  Victor Bustos; Maria V Pulina; Ashley Bispo; Alison Lam; Marc Flajolet; Fred S Gorelick; Paul Greengard
Journal:  Proc Natl Acad Sci U S A       Date:  2017-05-22       Impact factor: 11.205

5.  The role of presenilin cofactors in the gamma-secretase complex.

Authors:  Nobumasa Takasugi; Taisuke Tomita; Ikuo Hayashi; Makiko Tsuruoka; Manabu Niimura; Yasuko Takahashi; Gopal Thinakaran; Takeshi Iwatsubo
Journal:  Nature       Date:  2003-03-16       Impact factor: 49.962

6.  Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1.

Authors:  Y M Li; M Xu; M T Lai; Q Huang; J L Castro; J DiMuzio-Mower; T Harrison; C Lellis; A Nadin; J G Neduvelil; R B Register; M K Sardana; M S Shearman; A L Smith; X P Shi; K C Yin; J A Shafer; S J Gardell
Journal:  Nature       Date:  2000-06-08       Impact factor: 49.962

7.  Destabilization of beta-catenin by mutations in presenilin-1 potentiates neuronal apoptosis.

Authors:  Z Zhang; H Hartmann; V M Do; D Abramowski; C Sturchler-Pierrat; M Staufenbiel; B Sommer; M van de Wetering; H Clevers; P Saftig; B De Strooper; X He; B A Yankner
Journal:  Nature       Date:  1998-10-15       Impact factor: 49.962

Review 8.  Control of autophagy as a therapy for neurodegenerative disease.

Authors:  Harry Harris; David C Rubinsztein
Journal:  Nat Rev Neurol       Date:  2011-12-20       Impact factor: 42.937

9.  Pathogenic PS1 phosphorylation at Ser367.

Authors:  Masato Maesako; Jana Horlacher; Katarzyna M Zoltowska; Ksenia V Kastanenka; Eleanna Kara; Sarah Svirsky; Laura J Keller; Xuejing Li; Bradley T Hyman; Brian J Bacskai; Oksana Berezovska
Journal:  Elife       Date:  2017-01-30       Impact factor: 8.140

10.  Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease.

Authors:  R Sherrington; E I Rogaev; Y Liang; E A Rogaeva; G Levesque; M Ikeda; H Chi; C Lin; G Li; K Holman; T Tsuda; L Mar; J F Foncin; A C Bruni; M P Montesi; S Sorbi; I Rainero; L Pinessi; L Nee; I Chumakov; D Pollen; A Brookes; P Sanseau; R J Polinsky; W Wasco; H A Da Silva; J L Haines; M A Perkicak-Vance; R E Tanzi; A D Roses; P E Fraser; J M Rommens; P H St George-Hyslop
Journal:  Nature       Date:  1995-06-29       Impact factor: 49.962
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