Literature DB >> 28645243

Extended Periarterial Sympathectomy: Evaluation of Long-term Outcomes.

Collier S Pace1, Wyndell H Merritt1.   

Abstract

BACKGROUND: Periarterial sympathectomy is a proposed surgical treatment for patients with refractory Raynaud syndrome; however, there is debate regarding the indications and extent of dissection. Due to the segmental arterial sympathetic innervation, we favor an extended sympathectomy in concert with vein graft reconstruction of occluded vessels when necessary. The purpose of this study is to examine outcomes of extended periarterial sympathectomy in our patients.
METHODS: A retrospective chart review was performed on 46 patients who underwent 58 periarterial sympathectomies (12 bilateral) since 1981. The data collected include demographics, comorbidities, previous therapy, operative details, and surgical outcomes. In addition, we contacted available patients for a phone survey.
RESULTS: Of 58 cases, 68.9% were female, 29.3% were current smokers, and 58.6% had known connective tissue disease. Thirty-three vein graft reconstructions were performed with a long-term patency of 77.4%. Sustained improvement of ischemic pain was reported in 94.8% of cases, and 78% of patients with ulcers completely healed. For the most symptomatic fingertip, mean Semmes-Weinstein monofilament measurements improved from 4.15 preoperatively to 3.29 postoperatively ( P ≤ .05). Mean follow-up was 3.97 years. Of 10 patients contacted by telephone, all reported a decrease in frequency and severity of Raynaud attacks, while 9 reported a long-term decrease in pain an average of 11.6 years after surgery.
CONCLUSIONS: Extended periarterial sympathectomy is an effective and safe procedure for patients with refractory Raynaud syndrome. Our data demonstrate long-term improvement in ischemic pain and sensibility, along with a high rate of ulcer healing and patient satisfaction.

Entities:  

Keywords:  Raynaud’s; adventectomy; hand ischemia; periarterial sympathectomy

Mesh:

Year:  2017        PMID: 28645243      PMCID: PMC6081779          DOI: 10.1177/1558944717715119

Source DB:  PubMed          Journal:  Hand (N Y)        ISSN: 1558-9447


  31 in total

1.  Adventitial stripping of the radial and ulnar arteries in Raynaud's disease.

Authors:  Brigitta Balogh; W Mayer; M Vesely; S Mayer; H Partsch; H Piza-Katzer
Journal:  J Hand Surg Am       Date:  2002-11       Impact factor: 2.230

2.  Effect of perivascular sympathectomy on distal adrenergic innervation in the hands of monkeys.

Authors:  O Kaarela; T Raatikainen; S Carlson; T Huopaniemi; T Waris
Journal:  J Hand Surg Br       Date:  1991-11

Review 3.  Comprehensive management of Raynaud's syndrome.

Authors:  W H Merritt
Journal:  Clin Plast Surg       Date:  1997-01       Impact factor: 2.017

Review 4.  Role and rationale for extended periarterial sympathectomy in the management of severe Raynaud syndrome: techniques and results.

Authors:  Wyndell H Merritt
Journal:  Hand Clin       Date:  2014-11-25       Impact factor: 1.907

5.  Periarterial sympathectomy in scleroderma patients: intermediate-term follow-up.

Authors:  David S Ruch; Martha Holden; Beth Paterson Smith; Thomas L Smith; L Andrew Koman
Journal:  J Hand Surg Am       Date:  2002-03       Impact factor: 2.230

6.  Surgical treatment of systemic sclerosis--is it justified to offer peripheral sympathectomy earlier in the disease process?

Authors:  Arash Momeni; Sarah C Sorice; Antonia Valenzuela; David F Fiorentino; Lorinda Chung; James Chang
Journal:  Microsurgery       Date:  2015-01-14       Impact factor: 2.425

Review 7.  Raynaud's phenomenon and scleroderma. Dysregulated neuroendothelial control of vascular tone.

Authors:  B Kahaleh; M Matucci-Cerinic
Journal:  Arthritis Rheum       Date:  1995-01

8.  Superselective digital sympathectomy in Raynaud's phenomenon.

Authors:  D V Egloff; R P Mifsud; C Verdan
Journal:  Hand       Date:  1983-02

9.  The use of digital artery sympathectomy as a salvage procedure for severe ischemia of Raynaud's disease and phenomenon.

Authors:  T E McCall; D P Petersen; L B Wong
Journal:  J Hand Surg Am       Date:  1999-01       Impact factor: 2.230

Review 10.  Drawbacks of endoscopic thoracic sympathectomy.

Authors:  T A Ojimba; A E P Cameron
Journal:  Br J Surg       Date:  2004-03       Impact factor: 6.939

View more
  2 in total

Review 1.  Practical management of Raynaud's phenomenon - a primer for practicing physicians.

Authors:  Ahmad Ramahi; Michael Hughes; Dinesh Khanna
Journal:  Curr Opin Rheumatol       Date:  2022-06-09       Impact factor: 4.941

2.  Segmental branches emanating from saphenous nerve morphing into sympathetic trunks for innervation of saphenous artery and its clinical implication for arterial sympathectomy.

Authors:  Yun Xie; Fang Fang; Peisen Lin; Zhiming Zhang; Yuehong Zhuang
Journal:  Int Wound J       Date:  2021-06-04       Impact factor: 3.315

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.