Literature DB >> 28644706

Advance Care Planning and Palliative Care Integration for Patients Undergoing Hematopoietic Stem-Cell Transplantation.

Winnie S Wang1, Joseph D Ma1, Sandahl H Nelson1, Carolyn Revta1, Gary T Buckholz1, Carolyn M Mulroney1, Eric J Roeland1.   

Abstract

PURPOSE: Advance care planning (ACP) in hematopoietic stem-cell transplantation (HSCT) is challenging, given the potential for cure despite increased morbidity and mortality risk.The aim of this study was to evaluate ACP and palliative care (PC) integration for patients who underwent HSCT.
METHODS: A retrospective analysis was conducted and data were extracted from electronic medical records of patients who underwent HSCT between January 2011 and December 2015. Patients who received more than one transplant and who were younger than 18 years of age were excluded. The primary objective was to determine the setting and specialty of the clinician who documented the initial and final code status. Secondary objectives included evaluation of advance directive and/or completion of the Physician Orders for Life-Sustaining Treatment form, PC consultation, hospice enrollment, and location of death.
RESULTS: The study sample comprised 39% (n = 235) allogeneic and 61% (n = 367) autologous HSCTs. All patients except one (n = 601) had code status documentation, and 99.2% (n = 596) were initially documented as full code. Initial and final code status documentation in the outpatient setting was 3% (n = 17) and 24% (n = 143), respectively. PC consultation occurred for 19% (n = 114) of HSCT patients, with 83% (n = 95) occurring in the hospital. Allogeneic transplant type and age were significantly associated with greater rates of advance directive and/or Physician Orders for Life-Sustaining Treatment completion. Most patients (85%, n = 99) died in the hospital, and few were enrolled in hospice (15%, n = 17).
CONCLUSION: To our knowledge, this is the largest single-center study of ACP and PC integration for patients who underwent HSCT. Code status documentation in the outpatient setting was low, as well as utilization of PC and hospice services.

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Year:  2017        PMID: 28644706      PMCID: PMC6366810          DOI: 10.1200/JOP.2016.020321

Source DB:  PubMed          Journal:  J Oncol Pract        ISSN: 1554-7477            Impact factor:   3.840


  8 in total

1.  Characteristics and Impact of Post-Transplant Interdisciplinary Palliative Care Consultation in Older Allogeneic Hematopoietic Cell Transplant Recipients.

Authors:  Richard J Lin; Abigail G Cohen; Stacy M Stabler; Sean M Devlin; Theresa A Elko; Molly A Maloy; Beatriz Korc-Grodzicki; Koshy Alexander; Dana Kramer; Míriam Sanchez-Escamilla; Nerea Castillo Flores; Juliet N Barker; Christina Cho; Parastoo B Dahi; Boglarka Gyurkocza; Esperanza B Papadopoulos; Miguel-Angel Perales; Ioannis Politikos; Doris M Ponce; Craig S Sauter; Michael Scordo; Brian C Shaffer; Gunjan L Shah; Roni Tamari; James W Young; Ann A Jakubowski; Sergio A Giralt; Judith E Nelson
Journal:  J Palliat Med       Date:  2020-03-27       Impact factor: 2.947

2.  Transfusion practices at end of life for hematopoietic stem cell transplant patients.

Authors:  Winnie S Wang; Joseph D Ma; Sandahl H Nelson; Carolyn Revta; Gary T Buckholz; Carolyn Mulroney; Eric J Roeland
Journal:  Support Care Cancer       Date:  2017-12-28       Impact factor: 3.603

3.  Mapping the Landscape of Advance Care Planning in Adolescents and Young Adults Receiving Allogeneic Hematopoietic Stem Cell Transplantation: A 5-Year Retrospective Review.

Authors:  Brian W Pennarola; Abigail Fry; Laura Prichett; Andrea E Beri; Nirali N Shah; Lori Wiener
Journal:  Transplant Cell Ther       Date:  2021-12-20

4.  Advance Directive Utilization Is Associated with Less Aggressive End-of-Life Care in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation.

Authors:  Kathryn Cappell; Vandana Sundaram; Annie Park; Parveen Shiraz; Ridhi Gupta; Patricia Jenkins; Vyjeyanthi S J Periyakoil; Lori Muffly
Journal:  Biol Blood Marrow Transplant       Date:  2018-01-31       Impact factor: 5.742

Review 5.  Goal of a "Good Death" in End-of-Life Care for Patients with Hematologic Malignancies-Are We Close?

Authors:  Thomas M Kuczmarski; Oreofe O Odejide
Journal:  Curr Hematol Malig Rep       Date:  2021-04-16       Impact factor: 3.952

6.  Exploring the Expanded Role of Pharmacists in Advance Care Planning.

Authors:  Joseph D Ma; Alexandra Dullea; Chelsea Hagmann; Sarah Friedman; Michelle Russell; Arlene Cramer; Melanie Benn; Eric J Roeland
Journal:  JCO Oncol Pract       Date:  2021-01-08

Review 7.  What is known about palliative care in adult patients with allogeneic stem cell transplantation (allo-SCT)?

Authors:  Steffen T Simon; Anne Pralong; Michael Hallek; Christoph Scheid; Udo Holtick; Marco Herling
Journal:  Ann Hematol       Date:  2021-05-06       Impact factor: 3.673

8.  Allogeneic stem cell transplant recipients admitted to the intensive care unit during the peri-transplant period have unfavorable outcomes-results of a retrospective analysis from a German university hospital.

Authors:  Jorge Garcia Borrega; Jan-Michel Heger; Matthias Kochanek; Dennis A Eichenauer; Philipp Koehler; Udo Holtick; Michael Hallek; Christof Scheid; Boris Böll; Alexander Shimabukuro-Vornhagen
Journal:  Ann Hematol       Date:  2021-10-20       Impact factor: 3.673

  8 in total

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