Patricia Khashayar1,2, Hamidreza Aghaei Meybodi1, Mohsen Rezaei Hemami3, Bagher Larijani4. 1. Osteoporosis Research Center, Endocrinology and Metabolism Research Institute, Tehran University of Medical Sciences, Tehran, Iran. 2. Center for Microsystems Technology, Imec and Ghent University, Zwijnaarde, Ghent, Belgium. 3. Institute of HEHTA, University of Glasgow, Glasgow, UK. 4. Endocrinology and Metabolism Research Center (EMRC), Endocrinology and Metabolism Research Institute, Tehran University of Medical Sciences, 1411413137, Tehran, Iran. larijanib@tums.ac.ir.
Abstract
INTRODUCTION: As the high incidence of hypertension has been in conjunction with dramatic increase in the prevalence of obesity, many studies have suggested obesity as its underlying cause in diverse race and ethnic groups. AIM: The present study was designed to quantify the relationship between obesity variables and hypertension in Iranian population. A ROC curve analysis was also used to determine an optimal BMI cutoff for obesity with the aim of representing elevated incidence of hypertension in this population. METHODS: The study population comprised of apparently healthy men and women who participated in the Iranian Multi-centric Osteoporosis Studies (IMOS), a multi-centric cross-sectional study carried out in urban areas of five great cities (Tehran, Tabriz, Mashhad, Shiraz and Bushehr). The anthropometric (weight, height, waist and hip circumferences) and blood pressure measures were reported in some 5724 subjects. The influence of these factors on systolic and diastolic blood pressure was assessed based on a list-wise method. RESULTS: There was a significant difference in the studied subjects anthropometric (weight classes (BMI), WC and HC, and WHR) and blood pressure variables; age, gender and weight, however, were the only factors significantly influencing SBP and DBP. Furthermore, BMI showed a significant impact on the overall risk of developing hypertension. CONCLUSION: General obesity rather than abdominal obesity is directly linked with higher blood pressure levels in Iranian population.
INTRODUCTION: As the high incidence of hypertension has been in conjunction with dramatic increase in the prevalence of obesity, many studies have suggested obesity as its underlying cause in diverse race and ethnic groups. AIM: The present study was designed to quantify the relationship between obesity variables and hypertension in Iranian population. A ROC curve analysis was also used to determine an optimal BMI cutoff for obesity with the aim of representing elevated incidence of hypertension in this population. METHODS: The study population comprised of apparently healthy men and women who participated in the Iranian Multi-centric Osteoporosis Studies (IMOS), a multi-centric cross-sectional study carried out in urban areas of five great cities (Tehran, Tabriz, Mashhad, Shiraz and Bushehr). The anthropometric (weight, height, waist and hip circumferences) and blood pressure measures were reported in some 5724 subjects. The influence of these factors on systolic and diastolic blood pressure was assessed based on a list-wise method. RESULTS: There was a significant difference in the studied subjects anthropometric (weight classes (BMI), WC and HC, and WHR) and blood pressure variables; age, gender and weight, however, were the only factors significantly influencing SBP and DBP. Furthermore, BMI showed a significant impact on the overall risk of developing hypertension. CONCLUSION: General obesity rather than abdominal obesity is directly linked with higher blood pressure levels in Iranian population.
Entities:
Keywords:
Abdominal obesity; Blood pressure; Diastolic blood pressure; Hypertension; Obesity; Systolic blood pressure; Waist circumference; Waist to hip ratio
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