Literature DB >> 28642565

No evidence available on best therapies for postextraction haemorrhage.

Analia Veitz-Keenan1, James Keenan1.   

Abstract

Data sourcesThe review searched for published and ongoing trials in several databases with no restrictions on language or date of publication which included the Cochrane Oral Health Group Trials, Central Register of Controlled Trials, Medline, CINAHL, Embase, WHO Clinical Trials Registry Platform and clinical trial.gov.Study selectionRandomised clinical trials were considered that evaluated any intervention compared with another or with placebo for treating postoperative bleeding (PEB), post extraction. The primary outcome measures sought were: bleeding, amount of blood loss and cessation time required to control bleeding. The secondary outcomes: patient reported outcomes, such as pain or discomfort and adverse events.Data extraction and synthesisThree pairs of review authors independently screened the records.ResultsThe search strategy identified 1526 articles and abstracts. After removal of duplicates, 943 records were screened. Thirty-four full texts were examined. No trials met the inclusion criteria for the review.ConclusionsWe were unable to identify any reports of randomised controlled trials that evaluated the effects of different interventions for the treatment of post-extraction bleeding. In view of the lack of reliable evidence on this topic, clinicians must use their clinical experience to determine the most appropriate means of treating this condition, depending on patient-related factors. There is a need for well designed and appropriately conducted clinical trials on this topic, which conform to the CONSORT statement (www.consort-statement.org/).

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Year:  2017        PMID: 28642565     DOI: 10.1038/sj.ebd.6401241

Source DB:  PubMed          Journal:  Evid Based Dent        ISSN: 1462-0049


  6 in total

Review 1.  Topical application of tranexamic acid in anticoagulated patients undergoing minor oral surgery: A systematic review and meta-analysis of randomized clinical trials.

Authors:  Sara Juliana de Abreu de Vasconcellos; Thiago de Santana Santos; Daniele Machado Reinheimer; André Luis Faria-E-Silva; Maria de Fátima Batista de Melo; Paulo Ricardo Saquete Martins-Filho
Journal:  J Craniomaxillofac Surg       Date:  2016-10-13       Impact factor: 2.078

2.  Tranexamic acid mouthwash versus autologous fibrin glue in patients taking warfarin undergoing dental extractions: a randomized prospective clinical study.

Authors:  Glen Carter; Alastair Goss; John Lloyd; Ric Tocchetti
Journal:  J Oral Maxillofac Surg       Date:  2003-12       Impact factor: 1.895

3.  Hemostatic effect of n-butyl-2-cyanoacrylate (histoacryl) glue in warfarin-treated patients undergoing oral surgery.

Authors:  Fouad A Al-Belasy; Maged Z Amer
Journal:  J Oral Maxillofac Surg       Date:  2003-12       Impact factor: 1.895

4.  Dental management considerations for the patient with an acquired coagulopathy. Part 1: Coagulopathies from systemic disease.

Authors:  P B Lockhart; J Gibson; S H Pond; J Leitch
Journal:  Br Dent J       Date:  2003-10-25       Impact factor: 1.626

Review 5.  Antifibrinolytic therapy for preventing oral bleeding in patients with haemophilia or Von Willebrand disease undergoing minor oral surgery or dental extractions.

Authors:  Karin P M van Galen; Eveline T Engelen; Evelien P Mauser-Bunschoten; Robert J J van Es; Roger E G Schutgens
Journal:  Cochrane Database Syst Rev       Date:  2015-12-24

Review 6.  MANAGEMENT OF DENTAL EXTRACTIONS IN PATIENTS TAKING WARFARIN AS ANTICOAGULANT TREATMENT: A SYSTEMATIC REVIEW.

Authors:  Naamah Jacobs Weltman; Yasmeen Al-Attar; Johnson Cheung; David Philip Bruce Duncan; Ashley Katchky; Amir Azarpazhooh; Lusine Abrahamyan
Journal:  J Can Dent Assoc       Date:  2015       Impact factor: 1.316

  6 in total

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