| Literature DB >> 28641459 |
Jia-Ling Song1, Yao Yuan1, Ling-Hui Nie2, Bai-Lin Li1, Xu-Bing Qin1, Yan Li1, Jie-Wei Wu1, Sheng-Xiang Qiu1.
Abstract
One new ent-kaurane diterpene derivative (1), along with four known diterpenes, was isolated from the stems of Eurya chinensis R.Br. The structure of the new compound was established by extensive analysis of mass spectrometric and 1D and 2D NMR spectroscopic data. Compound 1 showed moderate anti-inflammatory activities with IC50 value of 8.12 μM. This is the first example of diterpenoids with 4-hydroxy-4-(2-hydroxyethyl)-1-hydroxyl-cyclohexanoyl substituent.Entities:
Keywords: Eurya chinensis; anti-inflammatory; derivative; diterpene
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Year: 2017 PMID： 28641459 DOI： 10.1080/14786419.2017.1343327
Source DB: PubMed Journal: Nat Prod Res ISSN： 1478-6419 Impact factor: 2.861