| Literature DB >> 28640800 |
Renee Stein1, Wei Song1, Mariette Marano1, Heta Patel1, Shubha Rao1, Elana Morris1.
Abstract
Identifying persons living with human immunodeficiency virus (HIV) who are unaware of their infection, linking them to HIV medical care, and reducing health disparities are important national goals (1). Of the 8,841 teens and young adults aged 13-24 years (collectively referred to as youths in this report) who received a diagnosis of HIV in 2014, 70% were young men who have sex with men (MSM) (2). In the same year, an estimated 52% of young MSM living with HIV were unaware of their infection compared with 15% among all persons living with HIV (3). An average of 22% of high school students who have had sexual intercourse and 33% of young adults (persons aged 18-24 years) reported ever receiving an HIV test (4). CDC recommends screening all persons aged 13-64 years, with annual rescreening for persons at high risk for HIV infection (5). Analysis of CDC-funded program data for youths submitted by 61 health departments in 2015 revealed that young MSM, who accounted for 83% of new diagnoses among all youths in non-health care facilities, received 28% of HIV tests.* The 2020 national goal is to link at least 85% of HIV-positive persons to HIV medical care within 30 days of diagnosis. In this analysis, 66% of youths who received positive test results for HIV infection were linked to care within 90 days of diagnosis. Increasing the number of youths at risk for HIV infection who are tested for HIV on a regular basis and ensuring that youths who receive positive test results for HIV are rapidly linked to and retained in appropriate medical care, including early initiation of antiretroviral therapy, are essential steps for reducing HIV infection in this vulnerable population.Entities:
Mesh:
Year: 2017 PMID: 28640800 PMCID: PMC5657796 DOI: 10.15585/mmwr.mm6624a2
Source DB: PubMed Journal: MMWR Morb Mortal Wkly Rep ISSN: 0149-2195 Impact factor: 17.586
HIV tests and newly diagnosed HIV infections among youths,* by selected characteristics — United States, Puerto Rico, and the U.S. Virgin Islands, 2015
| Characteristic | No. all HIV tests† | HIV tests† among youths | No. all newly diagnosed HIV infections§ | Newly diagnosed HIV infections§ among youths | ||||
|---|---|---|---|---|---|---|---|---|
| No. (%) | % of subgroup | No. (%) | % of subgroup | % Positive | aPR (95% CI) | |||
|
| ||||||||
| 13–19 | 221,338 | — | 26.4 | 415 | — | 14.0 | 0.19 | 0.51 (0.45–0.56)¶ |
| 20–24 | 617,004 | — | 73.6 | 2,558 | — | 86.0 | 0.41 | Reference |
| Male | 1,535,214 | 374,757 (24.4) | 45.0 | 10,531 | 2,661 (25.3) | 89.6 | 0.71 | Reference |
| Female | 1,457,341 | 453,198 (31.1) | 54.5 | 1,801 | 256 (14.2) | 8.6 | 0.06 | 0.09 (0.08–0.10)¶ |
| Transgender | 13,097 | 4,299 (32.8) | 0.5 | 187 | 52 (27.8) | 1.8 | 1.21 | 1.66 (1.26–2.18)¶ |
| White | 785,623 | 201,135 (25.6) | 25.6 | 2,657 | 440 (16.6) | 15.1 | 0.22 | 0.45 (0.41–0.50)¶ |
| Black or African American | 1,304,956 | 396,327 (30.4) | 50.4 | 5,843 | 1,727 (29.6) | 59.3 | 0.44 | Reference |
| Hispanic or Latino | 647,773 | 159,865 (24.7) | 20.3 | 3,253 | 626 (19.2) | 21.5 | 0.39 | 0.70 (0.63–0.77)¶ |
| Other†† | 87,176 | 21,081 (24.2) | 2.7 | 335 | 67 (20.0) | 2.3 | 0.32 | 0.50 (0.39–0.64)¶ |
| Multiple races | 21,015 | 8,510 (40.5) | 1.1 | 124 | 51 (41.1) | 1.8 | 0.60 | 0.99 (0.75–1.31) |
| Health care facility | 2,313,742 | 633,088 (27.4) | 75.8 | 7,623 | 1,665 (21.8) | 56.3 | 0.26 | 0.60 (0.56–0.65)¶ |
| Non–health care facility | 703,890 | 202,181 (28.7) | 24.2 | 4,860 | 1292 (26.6) | 43.7 | 0.64 | Reference |
|
| ||||||||
| Northeast | 480,665 | 125,699 (26.2) | 15.0 | 1,888 | 373 (19.7) | 12.6 | 0.30 | 0.73 (0.65–82)¶ |
| Midwest | 419,516 | 126,792 (30.2) | 15.1 | 1,549 | 439 (28.3) | 14.8 | 0.35 | 1.07 (0.96–1.20) |
| South | 1,689,548 | 488,561 (29.0) | 58.3 | 6,296 | 1687 (26.8) | 56.7 | 0.35 | Reference |
| West | 391,353 | 84,675 (21.7) | 10.1 | 2,564 | 431 (16.8) | 14.5 | 0.51 | 1.20 (1.07–1.35)§§ |
| U.S. dependent areas | 44,992 | 12,615 (28.0) | 1.5 | 250 | 43 (17.2) | 1.5 | 0.34 | 1.31 (0.95–1.80) |
|
| ||||||||
| High | 1,784,092 | 460,162 (25.8) | 54.9 | 8,421 | 1,923 (22.8) | 64.7 | 0.42 | Reference |
| Medium | 1,150,815 | 350,075 (30.4) | 41.8 | 3,830 | 981 (25.6) | 33.0 | 0.28 | 0.75 (0.69–0.82)¶ |
| Medium-low/Low | 91,167 | 28105 (30.8) | 3.4 | 296 | 69 (23.3) | 2.3 | 0.25 | 0.62 (0.49–0.80)¶ |
|
|
|
|
|
|
|
|
|
|
|
| ||||||||
| Men who have sex with men | 153,842 | 42,184 (27.4) | 28.2 | 2,891 | 883 (30.5) | 82.8 | 2.09 | Reference |
| Transgender persons | 5,445 | 1,860 (34.2) | 1.2 | 98 | 25 (25.5) | 2.3 | 1.34 | 0.64 (0.43–0.95)*** |
| Persons who inject drugs | 37,212 | 6,425 (17.3) | 4.3 | 254 | 26 (10.2) | 2.4 | 0.40 | 0.19 (0.13–0.29)¶ |
| Heterosexual males | 159,948 | 44,641 (27.9) | 29.9 | 464 | 75 (16.2) | 7.0 | 0.17 | 0.08 (0.06–0.10)¶ |
| Heterosexual females | 154,598 | 54,323 (35.1) | 36.4 | 312 | 57 (18.3) | 5.3 | 0.10 | 0.05 (0.04–0.07)¶ |
|
|
|
|
|
|
|
|
|
|
Abbreviations: aPR = adjusted prevalence ratio; HIV = human immunodeficiency virus.
* Youths are defined as teens and young adults aged 13–24 years.
† Valid HIV tests were defined as tests for which a test result (i.e., positive or negative) was known. Analyses excluded discordant and indeterminate results.
§ Included are persons who tested HIV-positive and did not report a previous positive test result, calculated using HIV surveillance verification (if available) or a person’s self-reported previous HIV status.
¶ Significant at p<0.001.
** Missing/invalid data were excluded. In the category “HIV tests among youths,” 6,088 (0.73%) records were excluded from gender, 51,424 (6.13%) from race/ethnicity, and 3,073 (0.37%) from test setting. In the category “newly diagnosed HIV infection among youths,” four (0.13%) were excluded from gender, 62 (2.09%) from race/ethnicity, and 16 (0.54%) from test setting.
Includes Asian, American Indian or Alaska Native, and Native Hawaiian or Pacific Islander.
§§ Significant at p<0.01.
Target population data are available only for tests performed in non–health care facilities and not for tests performed in health care facilities. Therefore, these data come from non–health care facilities only. Records that specified other target population and those with missing/invalid data were excluded. In the category “HIV tests among youths,” 33,703 (16.67%) records that specified other target population and 19,045 (9.42%) records with missing/invalid data were excluded. In the category “newly diagnosed HIV infection among youths,” 208 (16.10%) records that specified other target population and 18 (1.39%) records with missing/invalid data were excluded.
*** Significant at p<0.05.
Linkage to HIV medical care and interviews for partner services among newly diagnosed HIV-positive youths,* by selected characteristics — United States, Puerto Rico, and the U.S. Virgin Islands, 2015
| Characteristic | No. newly diagnosed HIV infections,† (% of total) | Linked to HIV medical care within 90 days of diagnosis§ | Interviewed for partner services¶ | ||||
|---|---|---|---|---|---|---|---|
| No. (% of subgroup) | aPR | No. missing linkage info. (%) | No (%) | aPR | No. missing linkage info. (%) | ||
|
| |||||||
| 13–19 | 415 (14.0) | 263 (63.4) | 0.95 (0.88–1.03) | 121 (29.2) | 258 (62.2) | 0.98 (0.90–1.06) | 88 (21.2) |
| 20–24 | 2,558 (86.0) | 1,692 (66.1) | Reference | 582 (22.8) | 1,613 (63.1) | Reference | 475 (18.6) |
|
| |||||||
| Male | 2,661 (86.9) | 1,758 (66.1) | Reference | 624 (23.5) | 1,693 (63.6) | Reference | 500 (18.8) |
| Female | 256 (8.6) | 163 (63.7) | 1.00 (0.91–1.10) | 68 (26.6) | 147 (57.4) | 0.92 (0.83–1.03) | 47 (18.4) |
| Transgender | 52 (1.8) | 31 (59.6) | 0.89 (0.72–1.10) | 11 (21.2) | 28 (53.9) | 0.86 (0.67–1.11) | 16 (30.8) |
|
| |||||||
| White | 440 (15.1) | 302 (68.6) | 1.08 (0.99–1.16) | 93 (21.1) | 275 (62.5) | 0.97 (0.88–1.05) | 74 (16.8) |
| Black or African American | 1,727 (59.3) | 1,085 (62.8) | Reference | 437 (25.3) | 1,074 (62.2) | Reference | 355 (20.6) |
| Hispanic or Latino | 626 (21.5) | 460 (73.5) | 1.04 (0.97–1.10) | 127 (20.3) | 424 (67.7) | 1.00 (0.94–1.08) | 89 (14.2) |
| Other | 67 (2.3) | 52 (77.6) | 1.11 (0.98–1.26) | 9 (13.4) | 40 (59.7) | 0.89 (0.73–1.08) | 13 (19.4) |
| Multiple races | 51 (1.8) | 32 (62.7) | 0.96 (0.78–1.18) | 15 (29.4) | 29 (56.9) | 0.88 (0.70–1.11) | 12 (23.5) |
|
| |||||||
| Health care facility | 1,665 (56.3) | 1,093 (65.6) | 1.00 (0.95–1.05) | 396 (23.8) | 1,052 (63.2) | 1.01 (0.95–1.07) | 302 (18.1) |
| Non–health care facility | 1,292 (43.7) | 853 (66.0) | Reference | 304 (23.5) | 807 (62.5) | Reference | 260 (20.1) |
|
| |||||||
| Northeast | 373 (12.5) | 292 (78.3) | 1.18 (1.11–1.27)§§ | 49 (13.1) | 245 (65.7) | 1.05 (0.97–1.15) | 81 (21.7) |
| Midwest | 439 (14.8) | 216 (49.2) | 0.81 (0.73–0.90)§§ | 157 (35.8) | 240 (54.7) | 0.85 (0.77–0.94) | 68 (15.5) |
| South | 1,687 (56.7) | 1,077 (63.8) | Reference | 423 (25.1) | 1,049 (62.2) | Reference | 383 (22.7) |
| West | 431 14.5) | 333 (77.3) | 1.16 (1.09–1.25)§§ | 68 1(5.8) | 301 (69.8) | 1.09 (1.01–1.18)¶¶ | 26 (6.0) |
| U.S. dependent areas | 43 (1.4) | 37 (86.0) | 1.50 (1.29–1.74)§§ | 6 14.0) | 36 (83.7) | 1.34 1.14–1.58)§§ | 5 (11.6) |
|
| |||||||
| High | 1,923 (64.7) | 1,48 (70.1) | Reference | 388 20.2) | 1,217 (63.3) | Reference | 353 (18.4) |
| Medium | 981 (33.0) | 545 (55.6) | 0.83 (0.78–0.89)§§ | 311 31.7) | 590 (60.1) | 0.99 0.92–1.06) | 208 (21.2) |
| Medium-low/Low | 69 (2.3) | 62 (89.9) | 1.30 (1.18–1.44)§§ | 4 5.8) | 64 (92.8) | 1.64 1.49–1.81)§§ | 2 (2.9) |
|
|
|
|
|
|
|
|
|
Abbreviations: aPR = adjusted prevalence ratio; HIV = human immunodeficiency virus.
* Youths are defined as teens and young adults aged 13–24 years.
† Includes persons who tested HIV-positive during the current test and were not found to be previously reported in the health department jurisdiction’s HIV surveillance system or self-reported not having a previous HIV-positive test result if surveillance system verification was not available.
§ Linkage to HIV medical care within 90 days of diagnosis means confirmation that the person attended their first HIV medical care appointment within 90 days of their diagnosis.
¶ “Partner services” is a process through which HIV-infected persons are interviewed to elicit information about their partners, who can then be confidentially notified of their possible exposure or potential risk and offered services that can protect the health of partners and prevent HIV transmission to others.
** Missing or invalid data were excluded. For the category “linked to HIV medical care,” three records were excluded from gender, 24 from race/ethnicity, and nine from test setting. For the category “interviewed for partner services,” three records were excluded from gender, 29 from race/ethnicity, and 12 from test setting.
Includes Asian, American Indian or Alaska Native, and Native Hawaiian or Pacific Islander.
§§ Significant at p<0.001.
¶¶ Significant at p<0.05.
Linkage to HIV medical care among previously diagnosed HIV-positive youths,* by selected characteristics, United States, Puerto Rico, and the U.S. Virgin Islands, 2015
| Characteristic | No. previously diagnosed HIV infections† | No. not in HIV medical care at time of current HIV test (%) | Previously diagnosed HIV-positive youths not in HIV medical care at time of this test who were then linked to care§ | ||
|---|---|---|---|---|---|
| No. (%) | aPR (95% CI) | No. missing linkage info (%) | |||
|
| |||||
| 13–19 | 216 | 197 (91.2) | 134 (68.0) | 1.02 (0.93–1.13) | 33 (16.8) |
| 20–24 | 1,695 | 1,552 (91.6) | 1,023 (65.9) | Reference | 350 (22.6) |
|
| |||||
| Male | 1,615 | 1,474 (91.3) | 986 (66.9) | Reference | 311 (21.1) |
| Female | 256 | 239 (93.4) | 149 (62.3) | 0.94 (0.85–1.05) | 62 (25.9) |
| Transgender | 31 | 27 (87.1) | 19 (70.3) | 1.02 (0.80–1.30) | 7 (25.9) |
|
| |||||
| White | 221 | 213 (96.4) | 156 (73.2) | 1.09 (0.99–1.20) | 40 (18.8) |
| Black or African American | 1,328 | 1,192 (89.8) | 775 (65.0) | Reference | 268 (22.5) |
| Hispanic or Latino | 243 | 232 (95.5) | 167 (72.0) | 1.06 (0.96–1.17) | 43 (18.5) |
| Other** | 26 | 26 (100.0) | 20 (76.9) | 1.07 (0.85–1.33) | 3 (11.5) |
| Multiple races | 15 | 14 (93.3) | 7 (50.0) | 0.72 (0.43–1.20) | 5 (35.7) |
|
| |||||
| Health care facility | 1,433 | 1,304 (91.0) | 868 (66.6) | 1.01 (0.93–1.10) | 280 (21.5) |
| Non-health care facility | 470 | 438 (93.2) | 287 (65.5) | Reference | 100 (22.8) |
|
| |||||
| Northeast | 129 | 112 (86.8) | 86 (76.8) | 1.30 (1.16–1.46)†† | 19 (17.0) |
| Midwest | 325 | 276 (84.9) | 203 (73.6) | 1.21 (1.11–1.33)†† | 42 (15.2) |
| South | 1,294 | 1,210 (93.5) | 742 (61.3) | Reference | 306 (25.3) |
| West | 156 | 144 (92.3) | 120 (83.3) | 1.33 (1.20–1.47)†† | 16 (11.1) |
| U.S. dependent areas | 7 | 7 (100.0) | 6 (85.7) | 1.29 (0.93–1.78) | 0 (0.0) |
|
| |||||
| High | 1043 | 942 (90.3) | 629 (66.8) | Reference | 188 (20.0) |
| Medium | 854 | 797 (93.3) | 521 (65.4) | 1.07 (1.00–1.15) | 193 (24.2) |
| Medium-low/Low | 14 | 10 (71.4) | 7 (70.0) | 0.95 (0.66–1.38) | 2 (20.0) |
|
|
|
|
|
|
|
Abbreviations: aPR = adjusted prevalence ratio; HIV = human immunodeficiency virus.
* Youths are defined as teens and young adults aged 13−24 years.
† Previously diagnosed HIV infections include those who tested HIV-positive during the current test and were found to be previously reported in the health department’s HIV surveillance system or self-reported having a previous HIV-positive test result if the surveillance system verification is not available.
§ Linkage to HIV medical care within 90 days of diagnosis means confirmation that the person attended their first HIV medical care appointment within 90 days of receiving their diagnosis.
¶ Missing or invalid data were excluded. In the category “previously diagnosed HIV infections,” nine records were excluded from gender, 78 from race/ethnicity, and eight from test setting. In the category “linked to care,” three records were excluded from gender, 32 from race/ethnicity, and two from test setting.
** Includes Asian, American Indian or Alaska Native, and Native Hawaiian or Pacific Islander.
†† Significant at p<0.001.