BACKGROUND: The purpose of this study was to evaluate the value of narrow band imaging (NBI) examination in the office for the diagnosis and follow-up of upper airway premalignant and malignant lesions. METHODS: Four hundred eighty lesions were evaluated with white light endoscopy (WLE) and NBI before a biopsy/excision. Additionally, 151 premalignant lesions were followed up without proven biopsy. Carcinoma-free survival was calculated. The learning curve was analyzed. RESULTS: Overall, the accuracy improved from 74.1% with WLE to 88.9% with NBI, being relevant in all anatomic subsites. The accuracy of NBI increased significantly with increasing experience (area under the curve [AUC] >0.9). After a follow-up of 25 months, 14 of 151 lesions (9.3%) converted into carcinoma. The 4-year carcinoma-free survival rate was 86.4%. The 4-year carcinoma-free survival rate differed significantly between lesions classified as benign/mild dysplasia versus those presenting as moderate/severe dysplasia (88.9% vs 73.5%; P = .018). CONCLUSION: The NBI provided a greater accuracy than WLE and showed promising usefulness for the follow-up of premalignant lesions.
BACKGROUND: The purpose of this study was to evaluate the value of narrow band imaging (NBI) examination in the office for the diagnosis and follow-up of upper airway premalignant and malignant lesions. METHODS: Four hundred eighty lesions were evaluated with white light endoscopy (WLE) and NBI before a biopsy/excision. Additionally, 151 premalignant lesions were followed up without proven biopsy. Carcinoma-free survival was calculated. The learning curve was analyzed. RESULTS: Overall, the accuracy improved from 74.1% with WLE to 88.9% with NBI, being relevant in all anatomic subsites. The accuracy of NBI increased significantly with increasing experience (area under the curve [AUC] >0.9). After a follow-up of 25 months, 14 of 151 lesions (9.3%) converted into carcinoma. The 4-year carcinoma-free survival rate was 86.4%. The 4-year carcinoma-free survival rate differed significantly between lesions classified as benign/mild dysplasia versus those presenting as moderate/severe dysplasia (88.9% vs 73.5%; P = .018). CONCLUSION: The NBI provided a greater accuracy than WLE and showed promising usefulness for the follow-up of premalignant lesions.
Authors: Adela Cordero Devesa; Miguel Vaca González; Franklin Mariño-Sánchez; Cecilia Pérez Martínez; Rubén Polo López; María Del Mar Medina González; Ignacio Cobeta Marco Journal: Eur Arch Otorhinolaryngol Date: 2018-09-06 Impact factor: 2.503
Authors: Muhammad Adeel Azam; Claudio Sampieri; Alessandro Ioppi; Pietro Benzi; Giorgio Gregory Giordano; Marta De Vecchi; Valentina Campagnari; Shunlei Li; Luca Guastini; Alberto Paderno; Sara Moccia; Cesare Piazza; Leonardo S Mattos; Giorgio Peretti Journal: Front Oncol Date: 2022-06-01 Impact factor: 5.738
Authors: Francesco Missale; Stefano Taboni; Cesare Piazza; Giorgio Peretti; Andrea Luigi Camillo Carobbio; Francesco Mazzola; Giulia Berretti; Andrea Iandelli; Marco Fragale; Francesco Mora; Alberto Paderno; Francesca Del Bon; Giampiero Parrinello; Alberto Deganello Journal: Eur Arch Otorhinolaryngol Date: 2021-03-12 Impact factor: 2.503