Literature DB >> 2863933

Central nervous system actions of somatostatin-related peptides.

M R Brown, L A Fisher.   

Abstract

Somatostatin-related peptides act within the central nervous system to influence adrenomedullary epinephrine secretion and thermoregulation. Cysteamine-induced depletion of brain somatostatin-related peptides or central administration of a somatostatin receptor antagonist alters adrenomedullary epinephrine secretion and thermoregulation in a predictable manner. The actions of cysteamine and the somatostatin receptor antagonist are reversed by administration of somatostatins into the central nervous system, supporting the hypothesis that endogenous brain somatostatin-related peptides are involved in the regulation of adrenomedullary epinephrine secretion and thermoregulation.

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Year:  1985        PMID: 2863933     DOI: 10.1007/978-1-4615-7886-4_13

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN: 0065-2598            Impact factor:   2.622


  5 in total

1.  Tissue-specific distribution of cross-linked somatostatin receptor proteins in the rat.

Authors:  C B Srikant; K K Murthy; Y C Patel
Journal:  Biochem J       Date:  1992-03-01       Impact factor: 3.857

2.  Selective central activation of somatostatin receptor 2 increases food intake, grooming behavior and rectal temperature in rats.

Authors:  A Stengel; M Goebel; L Wang; J Rivier; P Kobelt; H Monnikes; Y Tache
Journal:  J Physiol Pharmacol       Date:  2010-08       Impact factor: 3.011

Review 3.  Modulation of the adaptive response to stress by brain activation of selective somatostatin receptor subtypes.

Authors:  Andreas Stengel; Jean Rivier; Yvette Taché
Journal:  Peptides       Date:  2012-12-31       Impact factor: 3.750

Review 4.  Central actions of somatostatin-28 and oligosomatostatin agonists to prevent components of the endocrine, autonomic and visceral responses to stress through interaction with different somatostatin receptor subtypes.

Authors:  Andreas Stengel; Jean Rivier; Yvette Taché
Journal:  Curr Pharm Des       Date:  2013       Impact factor: 3.116

5.  Somatostatin receptor type 2 antagonism improves glucagon and corticosterone counterregulatory responses to hypoglycemia in streptozotocin-induced diabetic rats.

Authors:  Jessica T Y Yue; Elena Burdett; David H Coy; Adria Giacca; Suad Efendic; Mladen Vranic
Journal:  Diabetes       Date:  2011-11-21       Impact factor: 9.461

  5 in total

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