Htoo Kyaw1, Atif Z Shaikh1,2, Gokul Yaratha1, Misra Deepika1,2. 1. Department of Internal Medicine, The Brooklyn Hospital Center, Brooklyn, NY. 2. Division of Cardiology, The Brooklyn Hospital Center and Mount Sinai Beth Israel Hospital Center, New York, NY.
Abstract
BACKGROUND: Staphylococcus lugdunensis, a member of the coagulase-negative staphylococci (CoNS), has been recognized as a causal organism for infective endocarditis since the 1980s. Although most CoNS have an insidious and chronic nature, they are involved in a variety of systemic infections. S lugdunensis infective endocarditis is a rare entity but is as catastrophic as Staphylococcus aureus infective endocarditis and requires aggressive antibiotic therapy and, typically, valve replacement. S lugdunensis infective endocarditis-induced septic embolic cerebrovascular accident has rarely been reported in the literature. CASE REPORT: We present the case of a 63-year-old African American man who presented with sudden-onset aphasia and right-sided hemiplegia and was admitted for the management of cerebrovascular accident. Afterwards, he developed a fever and was found to have S lugdunensis bacteremia, with subsequent imaging revealing vegetations of the mitral valve. Despite being treated with culture-appropriate antibiotics, he remained persistently bacteremic and required surgical mitral valve replacement. CONCLUSION: S lugdunensis infective endocarditis is rare but can have a malignant course and requires early surgical intervention in most cases.
BACKGROUND:Staphylococcus lugdunensis, a member of the coagulase-negative staphylococci (CoNS), has been recognized as a causal organism for infective endocarditis since the 1980s. Although most CoNS have an insidious and chronic nature, they are involved in a variety of systemic infections. S lugdunensis infective endocarditis is a rare entity but is as catastrophic as Staphylococcus aureus infective endocarditis and requires aggressive antibiotic therapy and, typically, valve replacement. S lugdunensis infective endocarditis-induced septic embolic cerebrovascular accident has rarely been reported in the literature. CASE REPORT: We present the case of a 63-year-old African American man who presented with sudden-onset aphasia and right-sided hemiplegia and was admitted for the management of cerebrovascular accident. Afterwards, he developed a fever and was found to have S lugdunensis bacteremia, with subsequent imaging revealing vegetations of the mitral valve. Despite being treated with culture-appropriate antibiotics, he remained persistently bacteremic and required surgical mitral valve replacement. CONCLUSION: S lugdunensis infective endocarditis is rare but can have a malignant course and requires early surgical intervention in most cases.
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