| Literature DB >> 28635130 |
J Gorlin1,2, S Kinney2, M K Fung3, A Tinmouth4.
Abstract
For emergent warfarin reversal, four-factor prothrombin complex concentrates (4FPCCs) are recommended by many international guidelines. We surveyed international clinical sites including members of the Biomedical Excellence for Safer Transfusion (BEST) Collaborative. Most sites have emergent warfarin reversal protocols (53% use PCC, 25% use PCC+ plasma and 2% use plasma alone); however, variation between adjusted dosing and fixed dosing was observed.Entities:
Keywords: dosing strategy; prothrombin complex concentrate; protocol; warfarin reversal
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Year: 2017 PMID： 28635130 DOI： 10.1111/vox.12539
Source DB: PubMed Journal: Vox Sang ISSN： 0042-9007 Impact factor: 2.144