Literature DB >> 28634744

Gain-of-function SNPs in NLRP3 and IL1B genes confer protection against obesity and T2D: undiscovered role of inflammasome genetics in metabolic homeostasis?

Juliana de Moraes Rodrigues1, Dhemerson Souza de Lima1, Vinicius N C Leal1, Adriana A Bosco2, Valeria Sandrim3, Alessandra Pontillo4.   

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Year:  2017        PMID: 28634744     DOI: 10.1007/s12020-017-1343-0

Source DB:  PubMed          Journal:  Endocrine        ISSN: 1355-008X            Impact factor:   3.633


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  17 in total

Review 1.  Microbiome, metabolites and host immunity.

Authors:  Maayan Levy; Eran Blacher; Eran Elinav
Journal:  Curr Opin Microbiol       Date:  2016-11-22       Impact factor: 7.934

Review 2.  Integrative inflammasome activity in the regulation of intestinal mucosal immune responses.

Authors:  E Elinav; J Henao-Mejia; R A Flavell
Journal:  Mucosal Immunol       Date:  2012-12-05       Impact factor: 7.313

3.  Serum interleukin-1β in subjects with abdominal obesity and periodontitis.

Authors:  Anurag Satpathy; Shivamurthy Ravindra; Srinath Thakur; Sudhindra Kulkarni; Amit Porwal; Saurav Panda
Journal:  Obes Res Clin Pract       Date:  2015-02-11       Impact factor: 2.288

4.  Inflammasome is a central player in the induction of obesity and insulin resistance.

Authors:  Rinke Stienstra; Janna A van Diepen; Cees J Tack; Md Hasan Zaki; Frank L van de Veerdonk; Deshani Perera; Geoffrey A Neale; Guido J Hooiveld; Anneke Hijmans; Irene Vroegrijk; Sjoerd van den Berg; Johannes Romijn; Patrick C N Rensen; Leo A B Joosten; Mihai G Netea; Thirumala-Devi Kanneganti
Journal:  Proc Natl Acad Sci U S A       Date:  2011-08-29       Impact factor: 11.205

5.  Weight loss reduces interleukin-18 levels in obese women.

Authors:  Katherine Esposito; Alessandro Pontillo; Myriam Ciotola; Carmen Di Palo; Elisa Grella; Gianfranco Nicoletti; Dario Giugliano
Journal:  J Clin Endocrinol Metab       Date:  2002-08       Impact factor: 5.958

Review 6.  NLRPs, microbiota, and gut homeostasis: unravelling the connection.

Authors:  Lia Paola Zambetti; Alessandra Mortellaro
Journal:  J Pathol       Date:  2014-05-16       Impact factor: 7.996

7.  IL-18 Production from the NLRP1 Inflammasome Prevents Obesity and Metabolic Syndrome.

Authors:  Andrew J Murphy; Michael J Kraakman; Helene L Kammoun; Dragana Dragoljevic; Man K S Lee; Kate E Lawlor; John M Wentworth; Ajithkumar Vasanthakumar; Motti Gerlic; Lachlan W Whitehead; Ladina DiRago; Louise Cengia; Rachael M Lane; Donald Metcalf; James E Vince; Leonard C Harrison; Axel Kallies; Benjamin T Kile; Ben A Croker; Mark A Febbraio; Seth L Masters
Journal:  Cell Metab       Date:  2015-10-22       Impact factor: 27.287

8.  Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity.

Authors:  Jorge Henao-Mejia; Eran Elinav; Chengcheng Jin; Liming Hao; Wajahat Z Mehal; Till Strowig; Christoph A Thaiss; Andrew L Kau; Stephanie C Eisenbarth; Michael J Jurczak; Joao-Paulo Camporez; Gerald I Shulman; Jeffrey I Gordon; Hal M Hoffman; Richard A Flavell
Journal:  Nature       Date:  2012-02-01       Impact factor: 49.962

9.  Is interleukin-1β a culprit in macrophage-adipocyte crosstalk in obesity?

Authors:  Chen Bing
Journal:  Adipocyte       Date:  2015-01-07       Impact factor: 4.534

Review 10.  Association of all-cause mortality with overweight and obesity using standard body mass index categories: a systematic review and meta-analysis.

Authors:  Katherine M Flegal; Brian K Kit; Heather Orpana; Barry I Graubard
Journal:  JAMA       Date:  2013-01-02       Impact factor: 56.272

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  1 in total

1.  In COVID-19, NLRP3 inflammasome genetic variants are associated with critical disease and these effects are partly mediated by the sickness symptom complex: a nomothetic network approach.

Authors:  Michael Maes; Walton Luiz Del Tedesco Junior; Marcell Alysson Batisti Lozovoy; Mayara Tiemi Enokida Mori; Tiago Danelli; Elaine Regina Delicato de Almeida; Alexandre Mestre Tejo; Zuleica Naomi Tano; Edna Maria Vissoci Reiche; Andréa Name Colado Simão
Journal:  Mol Psychiatry       Date:  2022-01-12       Impact factor: 13.437

  1 in total

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